153899-55-9Relevant academic research and scientific papers
Synthesis and CNS-activity of spirocyclic pethidine and prodine analogs
Wuensch,Hoefner,Bauschke
, p. 513 - 518 (1993)
The bromoacetals 5a and 5b react with n-butyllithium and the piperidone 7 to yield the hydroxyacetals 8b and 8c, respectively. Cyclization of 8b and 8c followed by acid hydrolysis affords the spirocyclic hemiacetals 10b and 10c which are oxidized by PCC t
