153901-40-7

Upstream product

• 54705-80-5 8-chloro-6-phenyl-4H-<1,24>triazolo<4,3-a><1,5>benzodiazepin-5(6H)-one 
• 36985-45-2 8-chloro-4-(dimethylamino)-1,3-dihydro-1-phenyl-2H-1,5-benzodiazepin-2-one 
• 22316-55-8 N-desmethylclobazam 

Downstream Products

• 153901-47-4 [2-(8-Chloro-6-phenyl-6H-2,3,6,10b-tetraaza-benzo[e]azulen-5-ylsulfanyl)-ethyl]-dimethyl-amine 
• 153901-44-1 8-Chloro-5-methylsulfanyl-6-phenyl-6H-2,3,6,10b-tetraaza-benzo[e]azulene 
• 153901-51-0 (8-Chloro-6-phenyl-6H-2,3,6,10b-tetraaza-benzo[e]azulen-5-yl)-dimethyl-amine 
• 153901-52-1 8-Chloro-5-morpholin-4-yl-6-phenyl-6H-2,3,6,10b-tetraaza-benzo[e]azulene 
• 153901-53-2 8-Chloro-5-(4-methyl-piperazin-1-yl)-6-phenyl-6H-2,3,6,10b-tetraaza-benzo[e]azulene 

Relevant academic research and scientific papers

1,5-Benzodiazepines XI. 5-(Dialkylamino) or 5-(alkylthio) substituted 8-chloro-6-phenyl-6H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepines with anticonvulsant activity

The cyclocondensation of (dimethylamino)benzodiazepinones 3a,b with hydrazides yielded triazolobenzodiazepinones 4 which were treated with Lawesson's reagent to give thiolactams 5. The phase-transfer catalyzed (TEBA) alkylation of compounds 5 with suitabl