153941-58-3Relevant academic research and scientific papers
Reactions of 4-tosyl-2-phenyl-5-chloro-1,3-thiazole with N-, O-, and S-nucleophiles
Turov,Vinogradova,Brovarets,Drach
, p. 825 - 828 (2010)
The accessible two-center electrophilic substrate 4-tosyl-2-phenyl-5- chloro-1,3-thiazole reacts regioselectively with N-, O-, and S-nucleophiles to eliminate a chloride ion. The analog of this substrate, 4-tosyl-2-phenyl-5-p- chlorophenylsulphonyl-1,3-th
Reaction of 1-tosyl-2,2-dichloroenamines with the Lawesson's reagent
Turov,Vinogradova,Rusanov,Brovarets
experimental part, p. 848 - 852 (2012/09/22)
In the reaction of the available 1-tosyl-2,2-dihlorenamides with the Lawesson's reagent the derivatives of 4-tosyl-1,3-thiazole were shown to form containing a labile chlorine atom at the C5 position. This fact was used for the synthesis of a number of the previously unknown bifunctionally substituted 4,5-thiazoles.
