153973-14-9

Basic information

• Product Name: 2-Amino-N-phenylpropanamide hydrochloride
• Synonyms: 2-Amino-N-phenylpropanamide hydrochloride
• CAS NO: 153973-14-9
• Molecular Formula: C9H13ClN2O
• Molecular Weight: 200.66532
• Mol File: 153973-14-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Amino-N-phenylpropanamide hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-N-phenylpropanamide hydrochloride(153973-14-9)
• EPA Substance Registry System: 2-Amino-N-phenylpropanamide hydrochloride(153973-14-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 153973-14-9(Hazardous Substances Data)

Usage

Type of compound

A hydrochloride salt of 2-amino-N-phenylpropanamide

Derivation

Derived from the amino acid phenylalanine

Potential uses

Analgesic and anti-inflammatory agent, studied for the treatment of various types of pain and inflammation

Form

Hydrochloride salt

Properties

Stability and solubility

Status

Potential as a new drug candidate for the treatment of pain and inflammatory conditions.

Upstream product

• 126787-11-9 Tert-butyl N-[1-(phenylcarbamoyl)ethyl]carbamate 

Relevant articles and documents

Enantioselective Deaminative Alkylation of Amino Acid Derivatives with Unactivated Olefins

Herein, we report the first Ni-catalyzed enantioselective deaminative alkylation of amino acid and peptide derivatives with unactivated olefins. Key for success was the discovery of a new sterically encumbered bis(oxazoline) ligand backbone, thus offering a de novo technology for accessing enantioenriched sp3-sp3 linkages via sp3 C-N functionalization. Our protocol is distinguished by its broad scope and generality across a wide number of counterparts, even in the context of late-stage functionalization. In addition, an enantioselective deaminative remote hydroalkylation reaction of unactivated internal olefins is within reach, thus providing a useful entry point for forging enantioenriched sp3-sp3 centers at remote sp3 C-H sites.