153993-03-4

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 153993-08-9 5-(3,4-dimethoxyphenyl)pentan-2-one 
• 40173-90-8 3,4-dimethoxyphenethyl bromide 
• 153993-04-5 tert-Butyl-[4-(3,4-dimethoxy-phenyl)-1-methylene-butoxy]-dimethyl-silane 

Downstream Products

• 153993-08-9 5-(3,4-dimethoxyphenyl)pentan-2-one 
• 153993-04-5 tert-Butyl-[4-(3,4-dimethoxy-phenyl)-1-methylene-butoxy]-dimethyl-silane 

Relevant academic research and scientific papers

New Intramolecular α-Arylation Strategy of Ketones by the Reaction of Silyl Enol Ethers to Photosensitized Electron Transfer Generated Arene Radical Cations: Construction of Benzannulated and Benzospiroannulated Compounds

Efficient intramolecular α-arylation of ketones is achieved by the reaction of silyl enol ethers to photosensitized electron transfer (PET) generated arene radical cations. The arene radical cations are generated by one-electron transfer from the excited state of the methoxy-substituted arenes to ground-state 1,4-dicyanonaphthalene (DCN). This arylation strategy has provided the unique opportunity of constructing five- (23), six- (18), seven- (25) and eight-membered (27) benzannulated as well as benzospiroannulated (34) compounds. The explanation for the formation of 27 has been advanced by considering the proximity between the arene radical cation and silyl enol ether due to the self-coiling in the aqueous environment.