154015-16-4 Usage
Uses
Used in Organic Synthesis:
3,8-Dibromo-1,5-naphthyridine is utilized as a key building block in the synthesis of a wide range of pharmaceuticals and agrochemicals. Its chemical properties allow for the creation of complex organic molecules, making it an essential intermediate in the development of new compounds with specific therapeutic or pesticidal properties.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 3,8-Dibromo-1,5-naphthyridine serves as a valuable precursor for the production of various drugs. Its unique structure contributes to the design and synthesis of novel therapeutic agents, potentially leading to the discovery of new treatments for a variety of diseases and conditions.
Used in Antimicrobial and Antifungal Applications:
3,8-Dibromo-1,5-naphthyridine has been studied for its potential biological activities, including its effectiveness as an antimicrobial and antifungal agent. Its ability to inhibit the growth of certain microorganisms makes it a promising candidate for use in the development of new antibiotics and antifungal medications, addressing the growing need for novel treatments in the face of antibiotic resistance.
Check Digit Verification of cas no
The CAS Registry Mumber 154015-16-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,0,1 and 5 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 154015-16:
(8*1)+(7*5)+(6*4)+(5*0)+(4*1)+(3*5)+(2*1)+(1*6)=94
94 % 10 = 4
So 154015-16-4 is a valid CAS Registry Number.
154015-16-4Relevant academic research and scientific papers
Potential Antimalarials. XIX. Syntheses and Testing of &α-(Piperidin-2-yl)-&α-(7'-trifluoromethylquinolin-4'-yl)methanol and &α-(7-Bromo-1,5-naphthyridin-4-yl)-&α-(piperidin-2'-yl)methanol
Barlin, Gordon B.,Ireland, Stephen J.,Jiravinyu, Chuenjit,Nguyen, Trang M. T.,Kotecka, Barbara,Rieckmann, Karl H.
, p. 1695 - 1704 (2007/10/02)
The synthesis of the mefloquine analogue α-(piperidin-2-yl)-α-(7'-trifluoromethylquinolin-4'-yl)methanol (1) from 4-bromo-7-trifluoromethylquinoline and N-(hex-5-enyl)phthalimide through N-butyl>phthalimide 1''-oxide is reported. α-(7-Bromo-1,5-naphthyridin-4-yl)-α-(piperidin-2'-yl)methanol (2) was prepared by similar procedures.In tests against the K-1 isolate of Plasmodium falciparum, compound (1) proved the more active (IC 50 99 nM).
