15409-60-6 Usage
Uses
Used in Pharmaceutical Industry:
2-[(dimethylamino)methyl]cyclohexan-1-one is used as an intermediate in the synthesis of O-Desmethyl Tramadol Hydrochloride (D294750), which is an optically active metabolite of Tramadol. This application is significant because O-Desmethyl Tramadol Hydrochloride is known for its analgesic properties, making it a valuable compound in the development of pain relief medications.
Synthesis Reference(s)
Journal of the American Chemical Society, 98, p. 6715, 1976 DOI: 10.1021/ja00437a058Synthetic Communications, 14, p. 585, 1984 DOI: 10.1080/00397918408059581
Check Digit Verification of cas no
The CAS Registry Mumber 15409-60-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,4,0 and 9 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 15409-60:
(7*1)+(6*5)+(5*4)+(4*0)+(3*9)+(2*6)+(1*0)=96
96 % 10 = 6
So 15409-60-6 is a valid CAS Registry Number.
InChI:InChI=1/C4H5BrN2/c1-7-3-2-6-4(7)5/h2-3H,1H3
15409-60-6Relevant academic research and scientific papers
Stereocontrolled Syntheses of Mannich Bases and γ-Amino Alcohols
Risch, Nikolaus,Esser, Achim
, p. 233 - 238 (2007/10/02)
The reaction of enantiomerically pure SMP enamines 2 with iminium tetrachloroaluminates 3 yields optically active Mannich bases 4.Diastereoselective reduction of 4 gives γ-amino alcohols 5 with the desired configuration. Key Words: Mannich bases / Enamines / Iminium salts / γ-Amino alcohols
