154092-22-5

Basic information

• Product Name: Benzene, (4-fluoro-4-iodo-3-butenyl)-, (E)-
• CAS NO: 154092-22-5
• Molecular Formula: C10H10FI
• Molecular Weight: 276.092
• Mol File: 154092-22-5.mol

Chemical Properties

• CAS DataBase Reference: Benzene, (4-fluoro-4-iodo-3-butenyl)-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, (4-fluoro-4-iodo-3-butenyl)-, (E)-(154092-22-5)
• EPA Substance Registry System: Benzene, (4-fluoro-4-iodo-3-butenyl)-, (E)-(154092-22-5)

Safety Data

• Hazardous Substances Data: 154092-22-5(Hazardous Substances Data)

Relevant articles and documents

Synthesis of the multisubstituted halogenated olefins via cross-coupling of dihaloalkenes with alkylzinc bromides

The 1-fluoro-1-haloalkenes undergo Pd-catalyzed Negishi cross-couplings with primary alkylzinc bromides to give multisubstituted fluoroalkenes. The alkylation was trans-selective giving pure Z-fluoroalkenes in most cases. The highest yields were obtained with Pd2(dba)3 and PdCl 2(dppb) catalysts but the best stereochemical outcome was obtained with less reactive Pd(PPh3)4. The tertiary alkylzincs also produced desired fluoroalkenes in high yields. Coupling of β,β- dichlorostyrene with organozinc reagent resulted in the formation of monocoupled product.