154140-46-2

Upstream product

• 160531-47-5 N-Boc-3-iodo-N-methyl-D-tyrosine methyl ester 
• 24424-99-5 di-tert-butyl dicarbonate 
• 154140-45-1 N-Boc-N-methyl-O-TBS (R)-tyrosine methyl ester 
• 76757-90-9 N-(tert-butoxycarbonyl)-D-tyrosine methyl ester 
• 3410-66-0 D-tyrosine methyl ester 
• 556-02-5 tyrosine 

Downstream Products

• 154140-49-5 (S)-2-{(R)-2-[(2-tert-Butoxycarbonylamino-acetyl)-methyl-amino]-3-[4-(tert-butyl-dimethyl-silanyloxy)-3-iodo-phenyl]-propionylamino}-propionic acid methyl ester 
• 154140-47-3 (S)-2-{(R)-2-(tert-Butoxycarbonyl-methyl-amino)-3-[4-(tert-butyl-dimethyl-silanyloxy)-3-iodo-phenyl]-propionylamino}-propionic acid methyl ester 
• 154140-37-1 (S)-2-{(R)-2-[(2-Amino-acetyl)-methyl-amino]-3-[4-(tert-butyl-dimethyl-silanyloxy)-3-iodo-phenyl]-propionylamino}-propionic acid methyl ester 
• 154140-48-4 (S)-2-{(R)-3-[4-(tert-Butyl-dimethyl-silanyloxy)-3-iodo-phenyl]-2-methylamino-propionylamino}-propionic acid methyl ester 
• 126596-03-0 geodiamolide D 

Relevant academic research and scientific papers

Synthesis of the polyketide section of seragamide A and related cyclodepsipeptides via Negishi cross coupling

The synthesis of the polyketide section present in the potently cytotoxic marine cyclodepsipeptide jasplakinolide and related natural products, geodiamolides and seragamides, is reported. The key step is a Negishi cross coupling of (R)-(3-methoxy-2-methyl

Enantioselective Total Synthesis of Doliculide, a Potent Cytotoxic Cyclodepsipeptide of Marine Origin and Structure-Cytotoxicity Relationships of Synthetic Doliculide Congeners

The total synthesis of doliculide (1), a potent cytotoxic cyclodepsipeptide from the Japanese sea hare Dolabella auricularia, has been achieved.The key step of the synthesis is the construction of the sereogenic centers of a 15-carbon polyketide-derived d

Studies on cyclodepsipeptides - Part II : The total synthesis of jaspamide and geodiamolide-D

The total synthesis of cyclodepsipeptides jaspamide and geodiamolide D have been presented.