154140-56-4

Basic information

• Product Name: 1-(4,5-dimethoxy-2-nitrophenyl)diazoethane
• Synonyms: 1-(4,5-dimethoxy-2-nitrophenyl)diazoethane;1-(2-Diazoethyl)-4,5-diMethoxy-2-nitrobenzene
• CAS NO: 154140-56-4
• Molecular Weight: 0
• Mol File: 154140-56-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-(4,5-dimethoxy-2-nitrophenyl)diazoethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4,5-dimethoxy-2-nitrophenyl)diazoethane(154140-56-4)
• EPA Substance Registry System: 1-(4,5-dimethoxy-2-nitrophenyl)diazoethane(154140-56-4)

Safety Data

• Hazardous Substances Data: 154140-56-4(Hazardous Substances Data)

Usage

General Description

1-(4,5-dimethoxy-2-nitrophenyl)diazoethane is a chemical compound with the molecular formula C12H12N4O5. It is a diazo compound that is commonly used in organic synthesis and as a reagent in laboratory experiments. The compound is a diazoethane derivative and contains nitro and dimethoxy groups, which make it useful for various chemical reactions. It is known for its ability to undergo diazo coupling reactions, forming azo compounds. Additionally, it has been studied for its potential as a photoaffinity labeling reagent in biochemical research. The compound presents potential hazards due to its reactivity and should be handled with caution in laboratory settings.

InChI:InChI=1/C10H11N3O4/c1-6(12-11)7-4-9(16-2)10(17-3)5-8(7)13(14)15/h4-5H,1-3H3

Upstream product

• 4101-32-0 4',5'-dimethoxy-2'-nitroacetophenone 
• 123642-61-5 4,5-dimethoxy-2-nitroacetophenone hydrazone 

Relevant articles and documents

Caged agonist of P2Y1 and P2Y12 receptors for light-directed facilitation of platelet aggregation

We have prepared a caged form (MRS2703) of a potent dual agonist of the P2Y1 and P2Y12 nucleotide receptors, 2-MeSADP, by blocking the β-phosphate group with a 1-(3,4-dimethyloxyphenyl)eth-1-yl phosphoester. Although MRS2703 is itsel

Caged NADP and NAD

Provided are caged NADP and NAD compounds. The invention includes two types of caged NAD and NADP (NAD/P) analogs, each type having a different caging group binding at a different site on the molecule: Phosphate-caged DMNPE-NAD/P and nicotinamide-caged CNB-NAD/P. Both types of caged molecules are designed to be inactive in their caged configurations and activated upon photolysis of the caging group. In some applications, the different types of caged compounds may exhibit biochemically distinct activities. For example, "catalytically caged" NAD/P compounds according to the present invention may bind to an enzyme but not allow turnover prior to photolytic activation. This type of compound has the advantage, when used as a photolytic trigger for time-resolved studies, that it is bound to the enzyme active site prior to photolysis so that no additional diffusion or binding events are necessary to form the Michaelis complex. The present invention also provides NAD/P compounds which may be "affinity caged," having no interaction with the enzyme prior to photolysis. In addition, the invention provides methods of synthesizing caged NAD and NADP and methods of using these compounds in biomedical research applications. -GOVT PAR This invention was made with Government support under Grant (Contract) No. 04200 awarded by the National Science Foundation. The Government has certain rights to this invention.