154140-71-3

Basic information

• Product Name: 4-ETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE
• Synonyms: 4-ETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE
• CAS NO: 154140-71-3
• Molecular Formula: C11H15N
• Molecular Weight: 161.24
• Mol File: 154140-71-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 257.4°C at 760 mmHg
• Flash Point: 111.1°C
• Appearance: /
• Density: 0.949g/cm³
• Vapor Pressure: 0.0146mmHg at 25°C
• Refractive Index: 1.513
• CAS DataBase Reference: 4-ETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE(154140-71-3)
• EPA Substance Registry System: 4-ETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE(154140-71-3)

Safety Data

• Hazardous Substances Data: 154140-71-3(Hazardous Substances Data)

Usage

General Description

4-Ethyl-1,2,3,4-tetrahydroisoquinoline is a chemical compound that belongs to the class of tetrahydroisoquinolines. It is a heterocyclic compound with a five-membered ring containing four carbon atoms and one nitrogen atom. 4-ETHYL-1,2,3,4-TETRAHYDROISOQUINOLINE is commonly used as a building block in organic synthesis and drug discovery research. It has been studied for its potential pharmacological properties, including its role as a dopamine D2 receptor antagonist, which may have implications for treating neurological and psychiatric disorders. Additionally, 4-Ethyl-1,2,3,4-tetrahydroisoquinoline has been investigated for its potential anti-inflammatory and analgesic effects, making it a compound of interest in the field of medicinal chemistry.

InChI:InChI=1/C11H15N/c1-2-9-7-12-8-10-5-3-4-6-11(9)10/h3-6,9,12H,2,7-8H2,1H3

Upstream product

• 41219-10-7 4-ethylisoquinoline 
• 334706-50-2 2α-(o-bromophenyl)-4,4,7α-trimethyl-trans-octahydro-1,3-benzoxazine 
• 350508-48-4 N-(o-bromobenzyl)-2α-(1'-propenyl)-4,4,7α-trimethyl-trans-octahydro-1,3-benzoxazine 
• 350508-51-9 (5R,7aS,10R,11aR,12aS)-5-Ethyl-7,7,10-trimethyl-5,7a,8,9,10,11,11a,12a-octahydro-6H,7H-12-oxa-6a-aza-benzo[a]anthracene 
• 350508-57-5 (1R,2S,5R)-2-[1-((R)-4-Ethyl-3,4-dihydro-1H-isoquinolin-2-yl)-1-methyl-ethyl]-5-methyl-cyclohexanol 
• 350508-35-9 (3R,4aR,5aS,6R,12aS)-6-Ethyl-3,12,12-trimethyl-2,3,4,4a,6,11,12,12a-octahydro-1H,5aH-5-oxa-11a-aza-naphthacene 
• 334706-53-5 N-crotyl-2α-(o-bromophenyl)-4,4,7α-trimethyl-trans-octahydro-1,3-benzoxazine 
• 203190-43-6 N-(o-bromobenzyl)-8-aminomenthol 
• 6630-33-7 ortho-bromobenzaldehyde 
• 503822-35-3 (2R,4R)-2-(2-bromophenyl)-3-(but-2-enyl)-4-phenyl-1,3-oxazolidine 
• 503822-38-6 (3R,6R)-6-ethyl-3-phenyl-2,3,6,10b-tetrahydro-5H-oxazolo[2,3-a]isoquinoline 
• 503822-44-4 (1'R,4R)-4-ethyl-2-(2'-hydroxy-1'-phenylethyl)-1,2,3,4-tetrahydroisoquinoline 
• 1532-97-4 4-bromoisoquinoline 
• 31601-81-7 4-ethenylisoquinoline 

Relevant articles and documents

Aryl radical cyclization of chiral 3-allyl-2-(2-bromophenyl)-1,3-oxazolidines with tributyltin hydride

Stereoselective radical cyclization of (4R)-3-allyl-2-(2-bromophenyl)-4-phenyl-1,3-oxazolidine promoted by the initiator/tributyltin hydride system constructed the chiral oxazolo[2,3-a]tetrahydroisoquinoline skeleton. These tricyclic compounds were transf

Reduction of isoquinoline and pyridine-containing heterocycles with lithium triethylborohydride (Super-Hydride)

Isoquinolines, quinoline and pyridines are effectively reduced to 1,2,3,4-tetrahydroisoquinolines, 1,2,3,4-tetrahydroquinolines and piperidines respectively with lithium triethylborohydride (Super-Hydride). The mechanism of the reduction was explored by reduction of isoquinoline and pyridine with lithium triethylborodeuteride (Super-Deuteride).