154151-36-7 Usage
Description
2(4-BROMO-PHENYL)-ACETIMIDIC ACID ETHYL ESTER is an organic compound characterized by its chemical formula C10H11BrO2N. It is an ester derivative of acetimidic acid, featuring a bromine-substituted phenyl group. 2(4-BROMO-PHENYL)-ACETIMIDIC ACID ETHYL ESTER serves as an intermediate in the synthesis of pharmaceuticals and agrochemicals, and is utilized as a building block in organic chemistry for creating a variety of derivatives. Its structural features and potential biological activities also make it a candidate for applications in medicinal and pharmaceutical research.
Uses
Used in Pharmaceutical Industry:
2(4-BROMO-PHENYL)-ACETIMIDIC ACID ETHYL ESTER is used as an intermediate in the synthesis of various pharmaceuticals for its ability to be transformed into a range of different derivatives, contributing to the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 2(4-BROMO-PHENYL)-ACETIMIDIC ACID ETHYL ESTER is utilized as an intermediate in the production of agrochemicals, playing a role in the synthesis of compounds that can be used in pest control and crop protection.
Used in Organic Chemistry Research:
2(4-BROMO-PHENYL)-ACETIMIDIC ACID ETHYL ESTER is used as a building block in organic chemistry for its potential to undergo various chemical transformations, enabling the creation of new organic compounds for further research and applications.
Used in Medicinal Research:
2(4-BROMO-PHENYL)-ACETIMIDIC ACID ETHYL ESTER is also used in medicinal research due to its structural features and potential biological activities, making it a promising candidate for the development of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 154151-36-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,1,5 and 1 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 154151-36:
(8*1)+(7*5)+(6*4)+(5*1)+(4*5)+(3*1)+(2*3)+(1*6)=107
107 % 10 = 7
So 154151-36-7 is a valid CAS Registry Number.
154151-36-7Relevant articles and documents
Benzylimidazolines as h5-HT(1B/1D) serotonin receptor ligands: A structure-affinity investigation
Law, Ho,Dukat, Malgorzata,Teitler, Milt,Lee, David K. H.,Mazzocco, Lucia,Kamboj, Raj,Rampersad, Vik,Prisinzano, Thomas,Glennon, Richard A.
, p. 2243 - 2251 (2007/10/03)
Benzylimidazolines may represent a class of 5-HT(1D) ligands that has yet to be exploited. On the basis of a previous report that the 2- (substituted-benzyl)imidazoline α-adrenergic agonist oxymetazoline (8) binds with high affinity at calf brain 5-HT(1D) receptors, we explored the structure-affinity relationships of a series of related derivatives. Each of the aromatic substituents was removed and then reinstated in a systematic manner to determine the influence of the individual substituents on binding. It was found that all of the aromatic substituents of 8 act in concert to impart high affinity. However, although the 3-hydroxy group could be removed without significantly reducing affinity for h5-HT(1D) (i.e., human 5- HT(1Dα)) receptors, this modification reduced h5-HT(1B) (i.e., human 5- HT(1Dβ)) receptor affinity by nearly 50-fold. The 2,6-dimethyl groups also contribute to binding but seem to play a greater role for h5-HT(1B) binding than h5-HT(1D) binding. With the appropriate structural modifications, several compounds were identified that display 20- to > 100-fold selectivity for h5-HT(1D) versus h5-HT(1B) receptors. Preliminary functional data suggest that these compounds behave as agonists. Given that 5-HT(1D) agonists are currently being explored for their antimigraine action and that activation of h5-HT(1B) receptors might be associated with cardiovascular side effects, h5- HT(1D)selective agents may offer a new lead for the development of therapeutically efficacious agents.
