154152-56-4

Usage

Uses

Used in Food Industry:
2,4-Pentadienal, 5-(3,4-dimethoxyphenyl)-3-methyl-, (2E,4E)is used as a flavoring agent for enhancing the taste and aroma of various food products. Its strong odor and unique chemical properties make it a valuable ingredient in creating distinct flavors.
Used in Perfume Industry:
In the perfume industry, 2,4-Pentadienal, 5-(3,4-dimethoxyphenyl)-3-methyl-, (2E,4E)serves as a fragrance ingredient, contributing to the creation of various scents and perfumes. Its distinct odor and chemical composition allow it to be a key component in developing complex and appealing fragrances.
Used in Organic Synthesis:
2,4-Pentadienal, 5-(3,4-dimethoxyphenyl)-3-methyl-, (2E,4E)is utilized as a building block in organic synthesis for the development of various compounds. Its chemical structure makes it a versatile component in the synthesis of different organic molecules.
Used in Medicinal and Pharmaceutical Research:
Due to its chemical properties and structure, 2,4-Pentadienal, 5-(3,4-dimethoxyphenyl)-3-methyl-, (2E,4E)has potential applications in medicinal and pharmaceutical research. It can be explored for its possible contributions to the development of new drugs and therapeutic agents.
It is crucial to handle 2,4-Pentadienal, 5-(3,4-dimethoxyphenyl)-3-methyl-, (2E,4E)with care, as it may pose potential health hazards if not properly managed.

Upstream product

• 113949-27-2 (E)-4-(3,4-Dimethoxy-phenyl)-2-methyl-but-3-en-2-ol 
• 68-12-2 N,N-dimethyl-formamide 
• 41891-54-7 diethyl 3-(ethoxycarbonyl)-3-methylprop-2-en-yl phosphate 
• 82648-70-2 diethyl (3-cyano-2-methyl-2-trans-propenyl)phosphonate 
• 51318-62-8 ethyl (E)-4-bromo-3-methyl-2-butenoate 
• 65527-85-7 ethyl (E)-4-hydroxy-3-methyl-2-butenoate 
• 3621-52-1 (E)-ethyl 4-chloro-3-methylbut-2-enoate 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 15001-27-1 O-methyldehydrozingerone 
• 163192-35-6 ethyl (2E,4E)-5-(3,4-dimethoxyphenyl)-3-methylpenta-2,4-dienoate 
• 775579-91-4 (2E,4E)-5-(3,4-Dimethoxy-phenyl)-3-methyl-penta-2,4-dienenitrile 

Relevant academic research and scientific papers

Syntheses, antiproliferative activity and theoretical characterization of acitretin-type retinoids with changes in the lipophilic part

Acitretin analogs, incorporating changes in the lipophilic part, were efficiently synthesized from commercially available aromatic aldehydes or methyl ketones using the Wittig or Horner-Wadsworth-Emmons reaction. Their antiproliferative activity was evaluated against human breast MCF-7 epithelial cells. Analogs 3, 4, 8 and 11 exhibited strong, dose-dependent, antiproliferative activity on the tested cell line. Analog 3, incorporating three methoxy groups in the aromatic ring, exhibited the strongest inhibitory effect at 10 μM. High-level all electron conventional ab initio and density functional theory quantum chemical calculations were performed to obtain the molecular structure, electron charge distribution and polarization properties of all compounds of interest in this work. The most active analogs were planar and were characterized by larger dipole moments than the other synthesized molecules. Another factor of importance to the analysis of the activity of these molecules is the dipole polarizability.

Investigation of the spectral properties of the crowned retinals and bacteriorhodopsin analogs

The spectral properties of new crowned retinal analogs and their bacteriorhodopsin complexes are described.

STEREOSELECTIVE SYNTHESIS OF 5-ARYL-3-METHYL-2E,4E-PENTADIENALS

A series of 5-aryl-3-methyl-2E,4E-pentadienals were synthesized stereoselectively from 4-aryl-3E-buten-2-ones and methylmagnesium iodide followed by formylation of the obtained tertiary dimethylstyrylcarbinols by the formylating complex produced from dimethylformamide and phosphorus oxychloride.A synthesis of 2,3,6-trimethyl-4-methoxybenzaldehyde, starting from pseudocumene, is proposed.