154164-39-3 Usage
Uses
Used in Organic Synthesis:
1-(2-METHYL-4-NITRO-PHENYL)-1H-IMIDAZOLE is used as a key intermediate in the synthesis of various organic compounds. Its unique structure allows for the creation of a diverse range of molecules with potential applications in different industries.
Used in Pharmaceutical Research:
In the pharmaceutical industry, 1-(2-METHYL-4-NITRO-PHENYL)-1H-IMIDAZOLE is used as a starting material for the development of novel drugs. Its potential antimicrobial and antifungal properties make it a promising candidate for the treatment of various infections and diseases.
Used as an Antimicrobial Agent:
1-(2-METHYL-4-NITRO-PHENYL)-1H-IMIDAZOLE is used as an antimicrobial agent for its potential to combat bacterial and fungal infections. Its effectiveness in inhibiting the growth of harmful microorganisms makes it a valuable asset in the development of new antimicrobial drugs.
Used as an Antifungal Agent:
Similarly, 1-(2-METHYL-4-NITRO-PHENYL)-1H-IMIDAZOLE is used as an antifungal agent, leveraging its ability to inhibit fungal growth. This property is particularly useful in the creation of treatments for various fungal infections and conditions.
Used as an Enzyme Inhibitor:
1-(2-METHYL-4-NITRO-PHENYL)-1H-IMIDAZOLE has also been investigated for its potential use as an inhibitor of certain enzymes and biological processes. Its unique structure allows it to interact with specific targets, making it a valuable tool in the development of new therapeutic strategies.
Used in Research and Development:
In the field of research and development, 1-(2-METHYL-4-NITRO-PHENYL)-1H-IMIDAZOLE serves as an important compound for further exploration and experimentation. Its unique properties and potential applications make it an interesting subject for scientists and researchers working in various disciplines.
Check Digit Verification of cas no
The CAS Registry Mumber 154164-39-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,1,6 and 4 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 154164-39:
(8*1)+(7*5)+(6*4)+(5*1)+(4*6)+(3*4)+(2*3)+(1*9)=123
123 % 10 = 3
So 154164-39-3 is a valid CAS Registry Number.
154164-39-3Relevant academic research and scientific papers
6-(1H-imidazol-1-yl)-7-nitro-2,3 (1H,4H)-quinoxalinedione hydrochloride (YM90K) and related compounds: Structure-activity relationships for the AMPA- type non-NMDA receptor
Ohmori,Sakamoto,Kubota,Shimizu-Sasamata,Okada,Kawasaki,Hidaka,Togami,Furuya,Murase
, p. 467 - 475 (2007/10/02)
A novel series of quinoxalinediones possessing imidazolyl and related heteroaromatic substituents was synthesized and evaluated for their activity to inhibit [3H]AMPA binding from rat whole brain. From the structure- activity relationships, it was found that the 1H-imidazol-1-yl moiety could function as a bioisostere for the cyano and nitro groups, and that 6-(1H- imidazol-yl)-7-nitro-2,3(1H,4H)-quinoxalinedione (11) showed the most potent activity for the AMPA receptor. Compound 11 was evaluated for selectivity versus other excitatory amino acid receptors, and its action against AMPA at its receptor in the rat striatum was characterized. These data showed that compound 11 was a selective antagonist for the AMPA receptor with a K(i) value of 0.084 μM, being approximately equipotent with 2,3-dihydro-6-nitro- 7-sulfamoylbenzo(f)quinoxaline (3) (NBQX; K(i) = 0.060 μM). Compound 11 was also found to give protection against sound-induced seizure on DBA/2 mice at the minimum effective dose of 3 mg/kg ip (3; 10 mg/kg ip).
