154189-24-9 Usage
Uses
Used in Pharmaceutical Industry:
4-hydroxy-7-[2-[2-(3-phenethyloxypropylsulfonyl)ethylamino]ethyl]-3H-benzothiazol-2-one hydrochloride is used as a therapeutic agent for the treatment of symptoms associated with Chronic Obstructive Pulmonary Disease (COPD). Its application in this context is due to its potential pharmacological properties, which may help alleviate the symptoms and improve the quality of life for patients suffering from this condition.
Used in Drug Delivery Systems:
In the field of drug delivery, 4-hydroxy-7-[2-[2-(3-phenethyloxypropylsulfonyl)ethylamino]ethyl]-3H-benzothiazol-2-one hydrochloride may be utilized as a component in the development of novel drug delivery systems. Its unique chemical structure could potentially enhance the delivery, bioavailability, and therapeutic outcomes of various drugs, particularly those targeting respiratory conditions.
Brand Name:
Under the brand name Viozan, manufactured by AstraZeneca, 4-hydroxy-7-[2-[2-(3-phenethyloxypropylsulfonyl)ethylamino]ethyl]-3H-benzothiazol-2-one hydrochloride is marketed for the treatment of COPD symptoms, providing relief and support to patients in managing their condition.
Check Digit Verification of cas no
The CAS Registry Mumber 154189-24-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,1,8 and 9 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 154189-24:
(8*1)+(7*5)+(6*4)+(5*1)+(4*8)+(3*9)+(2*2)+(1*4)=139
139 % 10 = 9
So 154189-24-9 is a valid CAS Registry Number.
InChI:InChI=1/C22H28N2O5S2.ClH/c25-19-8-7-18(21-20(19)24-22(26)30-21)9-11-23-12-16-31(27,28)15-4-13-29-14-10-17-5-2-1-3-6-17;/h1-3,5-8,23,25H,4,9-16H2,(H,24,26);1H
154189-24-9Relevant academic research and scientific papers
Novel process
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, (2008/06/13)
The invention relates to a process for preparing benzothiazolone compounds having pharmacological activity and to intermediates used in their preparation.
7-(2-AMINOETHYL) BENZOTHIAZOLONES
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, (2008/06/13)
There are disclosed compounds of formula I, Ar--CH. sub.2 CH 2--NH--CR 1 R 2--X--Y I in whichAr represents a group, STR1 X represents a C. sub.1-12 alkylene chain optionally interrupted or terminated by one or more groups selected from--S(O) n--,--O--,--C(Z)--, CR 6 R. sup.7, phenylmethyne,--NR 8--,--CONH--,--NHCO--and--NHCONH--, Y represents an optionally substituted aryl or cycloalkyl group,Z represents O or S, R 1, R 2, R 5 and R 9 each independently represent hydrogen or alkyl C 1-6,R 3 and R 4 represent hydrogen, or R. sup.3 and R 4 together form a group--S--,--NR 9--or--CH 2--,R 6 and R 7 independently represent hydrogen, alkyl C 1-6, fluoro, cyano, or CF. sub.3, provided that at least one of R 6 and R 7 is other than hydrogen,R 8 represents hydrogen or alkyl C 1-6, or when X is interrupted or terminated by more than one--NR 8--group may together with another R 8 group form the chain--CH 2--CH 2--, andn represents 0, 1 or 2,and pharmaceutically acceptable derivatives thereof.Processes for their production and pharmaceutical compositions and methods of treatment involving their use are also described.
