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154212-56-3

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154212-56-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 154212-56-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,2,1 and 2 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 154212-56:
(8*1)+(7*5)+(6*4)+(5*2)+(4*1)+(3*2)+(2*5)+(1*6)=103
103 % 10 = 3
So 154212-56-3 is a valid CAS Registry Number.
InChI:InChI=1/C45H60Cl2O6.H3N/c1-25(2)8-6-9-26(3)35-14-15-36-32-13-12-30-20-27(16-18-44(30,4)37(32)17-19-45(35,36)5)10-7-11-31(28-21-33(42(50)51)40(48)38(46)23-28)29-22-34(43(52)53)41(49)39(47)24-29;/h11,21-27,30,32,35-37,48-49H,6-10,12-20H2,1-5H3,(H,50,51)(H,52,53);1H3/t26?,27-,30?,32?,35+,36?,37?,44-,45+;/m0./s1

154212-56-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-[1-(3-carboxy-5-chloro-4-hydroxyphenyl)-4-[(3S,5S,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl]but-1-enyl]-3-chloro-2-hydroxybenzoic acid

1.2 Other means of identification

Product number -
Other names TETRANOR-PGFM

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:154212-56-3 SDS

154212-56-3Relevant articles and documents

Design, Synthesis, and Biological Evaluation of Cosalane, a Novel Anti-HIV Agent Which Inhibits Multiple Features of Virus Reproduction

Cushman, Mark,Golebiewski, W. Marek,McMahon, James B.,Buckheit, Robert W.,Clanton, David J.,et al.

, p. 3040 - 3050 (2007/10/02)

Cosalane (3), a novel anti-HIV agent having a disalicylmethane unit linked to C-3 of cholestane by a three-carbon linker, was synthesized from commercially available starting materials by a convergent route.Cosalane proved to be a potent inhibitor of HIV with a broad range of activity against a variety of laboratory, drug-resistant, and clinical HIV-1 isolates, HIV-2, and Rauscher murine leukemia virus.The cytotoxicity of cosalane is relatively low as reflected by an in vitro therapeutic index of > 100.Although cosalane inhibits HIV-1 reverse transcriptase and protease, time of addition experiments indicate that it prevents the cytopathic effect of HIV by acting earlier than reverse transcription in the viral replication cycle.The available evidence indicates that the primary mechanism of action of cosalane involves inhibition of gp 120-CD4 binding as well as inhibition of a postattachment event prior to reverse transcription.

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