154220-75-4Relevant academic research and scientific papers
A convenient synthesis of antiviral acyclic C-nucleosides incorporating 1,3,4-thiadiazine nucleus as a nucleobase
Yadav,Singh,Dubey
, p. 674 - 677 (2007/10/03)
Adducts 4a-d obtained by nucleophilic addition of sulphenylated dimethyl sulphoxide derivatives 2a,b to glucose thiosemicarbazones 3a,b undergo intramolecular cyclisation, involving methanesulphinyl leaving group, with 90% H2SO4 and Pummerer rearrangement with glacial acetic acid to yield acyclic C-nucleosides, 2-arylamino-6-(5-aryl-1,3,4-thiadiazol-2-ylthio)-5-(D-glucopentyl)-4H,5,6- dihydro-1,3,4-thiadiazines 6a-d and 2-arylamino-6-(5-aryl-1,3,4-thiadiazol-2-ylthio)-5-(D-glucopentyl)-6- methylthio-4H,5,6-dihydro-1,3,4-thiadiazines 7a-d, respectively.
A NEW CYCLISATION OF SULPHENYLATED DMSO AND THIOSEMICARBAZONE ADDUCTS INVOLVING METHANESULPHINYL LEAVING GROUP
Yadav, Lal Dhar S.,Sharma, Sangeeta
, p. 11 - 16 (2007/10/02)
Adducts 4 obtained by nucleophilic addition of sulphenylated DMSO, 2, to thiosemicarbazones 3 underwent a new intramolecular cyclisation to 6-sulphenylated 2-amino-5-aryl-1,3,4-thiadiazines, 6, involving the loss of the acid-labile methanesulphinyl leavin
A new cyclisation involving a methanesulfinyl leaving group yielding 6-sulfenylated 2-amino-4H-5,6-dihydro-1,3,4-thiadiazines
Yadav,Sharma
, p. 864 - 866 (2007/10/02)
Nucleophilic addition of sulfenylated dimethyl sulfoxide derivatives to thiosemicarbazones 3 followed by a new intramolecular cyclisation involving an acid labile methanesulfinyl leaving group yields 6-sulfenylated 2-amino-5-aryl-4H,5,6-dihydro-1,3,4-thia
