1542260-41-2

Upstream product

• 1542260-38-7 2′,3′,5′-tri-O-benzoyl-2′,3',4',5',5''-pentadeuterium-β-D-ribofuranosyl-N⁴-benzoylcytidine 
• 1824-96-0 methyl ribofuranoside 

Downstream Products

• 1542260-44-5 5'-O-dimethoxytrityl-2',3',5'-trihydroxy-2',3',4',5',5-pentadeuterium-β-D-ribofuranosyl-N⁴-benzoyl-cytidine 
• 1542260-57-0 5'-O-dimethoxytrityl-2'-O-terbutyldimethylsilyl-3'-O-succinyl-pyridinium 2',3',5'-trihydroxy-2',3',4',5',5-pentadeuterium-β-D-ribofuranosyl-N⁴-benzoyl-cytidine 
• 1542260-53-6 5'-O-dimethoxytrityl-2'-O-terbutyldimethylsilyl-3'-N,N-diisopropyl-O-(2-cyanoethyl)phosphoramidite-2',3',5'-trihydroxy-2',3',4',5',5-pentadeuterium-β-D-ribofuranosyl-N⁴-benzoyl-cytidine 
• 1542260-47-8 5′-O-dimethoxytrityl-2′-O-terbutyldimethylsilyl-3′-O-succinyl pyridinium salt-2′,3',4',5',5''-pentadeuterium-β-D-ribofuranosyl-N⁴-benzoylcytidine 
• 1542260-50-3 5'-O-dimethoxytrityl-3'-O-terbutyldimethylsilyl-2',3',5'-trihydroxy-2',3',4',5',5-pentadeuterium-β-D-ribofuranosyl-N⁴-benzoyl-cytidine 

Relevant academic research and scientific papers

Synthesis of deuterated ribo nucleosides, N-protected phosphoramidites, and oligonucleotides

The present invention is directed towards the synthesis of high purity deuterated sugars, deuterated phosphoramidites, deuterated nucleobases, deuterated nucleosides, deuterated oligonucleotides, and deuterated RNA's of defined sequences which can exhibit biochemically useful and biologically valuable properties, thus having potential for therapeutic uses.

Synthesis of deuterated ribo nucleosides N-protected phosphoramidites, and oligonucleotides

The present invention is directed towards the synthesis of high purity deuterated sugars, deuterated phosphoramidites, deuterated nucleobases, deuterated nucleosides, deuterated oligonucleotides, and deuterated RNA's of defined sequences which can exhibit biochemically useful and biologically valuable properties, thus having potential for therapeutic uses.