154227-74-4Relevant academic research and scientific papers
Investigation of Isothiocyanate Addition to Alkylidene Derivatives of Malononitrile and Cyanoacetic Acid Esters
Hehemann, David G.,Winnik, Witold
, p. 887 - 892 (2007/10/02)
Addition of arylisothiocyanates to active methylene compounds leads to a variety of compounds depending of the structure of the starting material and conditions used to conduct the addition.Addition of arylisothiocyanate to 1c leads to a pyridopyrimidine resulting from addition of a second mole of cyanate to the initial adduct.Addition of arylisothiocyanate to 1b led to a mixture of pyridine and thiopyran adducts, while addition to 1a led to open chain structures.
