1542276-01-6

Basic information

• Product Name: (4-fluorophenyl)-[6-(4-fluorophenyl)-7-(1H-indol-3-yl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrimidin-8-yl]methanone
• Synonyms: (4-fluorophenyl)-[6-(4-fluorophenyl)-7-(1H-indol-3-yl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrimidin-8-yl]methanone
• CAS NO: 1542276-01-6
• Molecular Weight: 453.491
• Mol File: 1542276-01-6.mol

Chemical Properties

• CAS DataBase Reference: (4-fluorophenyl)-[6-(4-fluorophenyl)-7-(1H-indol-3-yl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrimidin-8-yl]methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (4-fluorophenyl)-[6-(4-fluorophenyl)-7-(1H-indol-3-yl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrimidin-8-yl]methanone(1542276-01-6)
• EPA Substance Registry System: (4-fluorophenyl)-[6-(4-fluorophenyl)-7-(1H-indol-3-yl)-1,2,3,4-tetrahydropyrrolo[1,2-a]pyrimidin-8-yl]methanone(1542276-01-6)

Safety Data

• Hazardous Substances Data: 1542276-01-6(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 447-43-8 1-(4-fluorophenyl)-2,2-dihydroxyethan-1-one 
• 251940-05-3 1-(4-fluoro-phenyl)-2-(tetrahydro-pyrimidin-2-ylidene)-ethanone 

Relevant articles and documents

Three-component domino reaction synthesis of highly functionalized bicyclic pyrrole derivatives

An efficient one-pot synthesis of highly functionalized bicyclic pyrrole derivatives by a three-component domino reaction of heterocyclic ketene aminals (HKAs), arylglyoxal monohydrate, and indoles in ethanol medium catalyzed by acetic acid is described. In this procedure, three sigma bonds were formed simultaneously. The present synthesis features excellent regio-selectivity, easy purification as well as simple starting materials.