154230-45-2

Upstream product

• 154230-33-8 [(2R,3S,5R)-5-(3-Benzyloxymethyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-2-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-furan-3-yloxy]-acetic acid ethyl ester 
• 154230-32-7 5'-O-tert-butyldiphenylsilyl-N³-benzyloxymethyl-2'-deoxythymidine 
• 101527-40-6 5'-O-tert-butyldiphenylsilylthymidine 
• 3587-60-8 Benzyloxymethyl chloride 
• 154230-34-9 3-((Benzyloxy)methyl)-3'-O-(2-hydroxyethyl)-5'-O-(tert-butyldiphenylsilyl)thymidine 
• 944474-95-7 (3S,5R)-benzoic acid 2-acetoxy-5-(3-benzyloxymethyl-5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 

Downstream Products

• 166955-07-3 Benzoic acid (2S,3S,5R)-2-{2-[(2R,3S,5R)-2-(tert-butyl-diphenyl-silanyloxymethyl)-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yloxy]-ethoxy}-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 

Relevant academic research and scientific papers

Nucleic Acid Mimics. Synthesis of Ethylene Glycol- and Propoxy-Linked Thymidyl-Tetrahydrofuranylthymine Dimers via a Vorbrueggen-Type Glycosylation Reaction

Two thymidyl-tetrahydrofuranylthymine dimers, 15 and 16, were synthesized stereospecifically in good yield via a Vorbrueggen-type reaction between glycol ether 4 or propoxy alcohol 7 and acetate 12.