154244-33-4Relevant academic research and scientific papers
Heterolignanolides. Furo- and thieno-analogues of podophyllotoxin and thuriferic acid
Ramos, Angel C,Peláez, Rafael,Luis López, Jose,Caballero, Esther,Medarde, Manuel,San Feliciano, Arturo
, p. 3963 - 3977 (2001)
The conjugate addition-alkylation to 5H-furan-2-one followed by cyclization and controlled epimerizations have been applied to the synthesis of new furo- and thieno-lignan analogues. Podophyllotoxin and thuriferic acid heteroanalogues have been obtained by this methodology, as representative members of these families.
Synthesis and cytotoxic activities of analogues of thuriferic acid
Madrigal, Blanca,Puebla, Pilar,Ramos, Angel,Pelaez, Rafael,Gravalos, Dolores,Caballero, Esther,Medarde, Manuel
, p. 303 - 312 (2007/10/03)
Several analogues of thuriferic acid and derivatives, with the 3,4-methylenedioxyphenyl ring replaced by naphthalene, furan, thiophene and carbazole ring systems, have been prepared. The synthetic strategy is based on a conjugate addition-alkylation metho
