154244-34-5Relevant academic research and scientific papers
Synthesis and cytotoxic activities of analogues of thuriferic acid
Madrigal, Blanca,Puebla, Pilar,Ramos, Angel,Pelaez, Rafael,Gravalos, Dolores,Caballero, Esther,Medarde, Manuel
, p. 303 - 312 (2007/10/03)
Several analogues of thuriferic acid and derivatives, with the 3,4-methylenedioxyphenyl ring replaced by naphthalene, furan, thiophene and carbazole ring systems, have been prepared. The synthetic strategy is based on a conjugate addition-alkylation metho
Heterolignanolides. Furo- and thieno-analogues of podophyllotoxin and thuriferic acid
Ramos, Angel C,Peláez, Rafael,Luis López, Jose,Caballero, Esther,Medarde, Manuel,San Feliciano, Arturo
, p. 3963 - 3977 (2007/10/03)
The conjugate addition-alkylation to 5H-furan-2-one followed by cyclization and controlled epimerizations have been applied to the synthesis of new furo- and thieno-lignan analogues. Podophyllotoxin and thuriferic acid heteroanalogues have been obtained by this methodology, as representative members of these families.
