154256-01-6Relevant academic research and scientific papers
Cycloadditions of cephalosporins. The formation of [4 + 2] adducts with 5- membered heterocycles
Elliott,Nicholson,Peaker,Takle,Tyler,White
, p. 1606 - 1607 (1994)
The cephalosporin triflate 1, and its sulfoxides 4 and 5, react with furan in the presence of a base to give [4 + 2] cycloadducts; the regiochemistry of the addition is determined by the oxidation state of the cephalosporin.
Cycloadditions of cephalosporins. A comprehensive study of the reaction of cephalosporin triflates with olefins, acetylenes, and dienes to form [2 + 2] and [4 + 2] adducts
Elliott, Richard L.,Nicholson, Neville H.,Peaker, Fiona E.,Takle, Andrew K.,Richardson, Christine M.,Tyler, John W.,White, Janet,Pearson, Michael J.,Eggleston, Drake S.,Haltiwanger, R. Curtis
, p. 4998 - 5016 (2007/10/03)
Novel polycyclic cephalosporins are formed by the reaction of cephalosporin triflates with various unsaturated compounds in the presence of Hunigs base. 2,3-Fused cyclobutane and cyclobutene cephems are obtained with olefins and acetylenes, respectively,
