154261-06-0Relevant academic research and scientific papers
Aza-Claisen rearrangements initiated by acid-catalyzed Michael addition
Vedejs, Edwin,Gingras, Marc
, p. 579 - 588 (1994)
The reaction of allylic amines with dimethyl acetylenedicarboxylate is subject to protic acid catalysis and affords 15, the product of Michael addition and aza-Claisen rearrangement. The sequence involves Michael addition of 4c or 19-21 to generate an int
