154269-17-7Relevant academic research and scientific papers
Quinolonecarboxylic acid derivatives
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, (2008/06/13)
Presented is a novel quinolonecarboxylic acid derivative of the formula I and its pharmaceutically acceptable salt: STR1 wherein R1 is hydrogen, halogen or lower alkoxy, R2 is hydrogen, lower alkyl, lower alkoxy, --NH2, --NHCOCH3 or halogen, R3 is lower alkyl, and z is a group represented by the formula II or III: STR2 wherein R4 and R5 are identical or different and are hydrogen or lower alkyl. A method of preparation of these compound and a method of treatment of diseases caused by bacterial infection are also presented.
Steroid derivatives
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, (2008/06/13)
This invention provides a novel steroid derivative having the structure of an ester between the carboxyl group of a quinolonecarboxylic acid and the alcoholic hydroxyl group in 21-position of asteroid compound, which has the following formula (I) (wherein R is a hydrogen atom, a methyl group or a hydroxyl group) or a pharmacologically acceptable salt thereof. STR1 The compound of this invention has high antibacterial activity and antiinflammatory activity.
