1542712-01-5

Basic information

• Product Name: 1-(4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-2-cyclopropyl-1H-indole-4-carbonitrile
• Synonyms: 1-(4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-2-cyclopropyl-1H-indole-4-carbonitrile
• CAS NO: 1542712-01-5
• Molecular Weight: 421.502
• Mol File: 1542712-01-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-2-cyclopropyl-1H-indole-4-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-2-cyclopropyl-1H-indole-4-carbonitrile(1542712-01-5)
• EPA Substance Registry System: 1-(4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-2-cyclopropyl-1H-indole-4-carbonitrile(1542712-01-5)

Safety Data

• Hazardous Substances Data: 1542712-01-5(Hazardous Substances Data)

Upstream product

• 944902-88-9 2,4-dichloro-7,8-dihydro-5H-pyrano[4,3-d]pyrimidine 
• 1478126-83-8 7, 8-dihydro-5H-pyrano[4,3-d]pyrimidine-2,4-diol 
• 1542711-49-8 methyl 4-amino-5,6-dihydro-2H-pyran-3-carboxylate 
• 127956-11-0 4-oxotetrahydro-2H-pyran-3-carboxylic acid methyl ester 
• 29943-42-8 Tetrahydro-4H-pyran-4-one 
• 1542711-93-2 2-(2-cyclopropyl-2-oxoethyl)-3-nitrobenzonitrile 
• 1542711-55-6 N-benzyl-2-chloro-7,8-di-hydro-5H-pyrano[4,3-d]pyrimidin-4-amine 
• 1542711-91-0 tert-butyl 2-(2-cyano-6-nitrophenyl)-3-cyclopropyl-3-oxopropanoate 
• 134302-07-1 tert-butyl 3-cyclopropyl-3-oxopropanoate 

Downstream Products

• 1542706-80-8 1-(4-(benzylamino)-7,8-dihydro-5H-pyrano[4,3-d]pyrimidin-2-yl)-2-cyclopropyl-1H-indole-4-carboxamide 

Relevant articles and documents

FUSED PYRIMIDINES AS INHIBITORS OF p97 COMPLEX

Fused pyrimidine compounds having a saturated, unsaturated or aromatic A ring fused to a pyrimidine ring and having a complex substituents at the 2 position and a substituted amine at the 4 position of the pyrimidine ring as well as optional aliphatic, functional and/or aromatic components substituted at other positions of the pyrimidine ring and A ring are disclosed. These compounds are inhibitors of the AAA proteasome complex containing p97 and are effective medicinal agents for treatment of diseases associated with p97 bioactivity such as cancer.