154273-16-2Relevant academic research and scientific papers
Synthesis of 4-phosphono (difluoromethyl)-D,L-phenylalanine and N-boc and N-Fmoc derivatives suitably protected for solid-phase synthesis of nonhydrolyzable phosphotyrosyl peptide analogues
Burkejr Jr., Terrence R.,Smyth, Mark S.,Otaka, Akira,Roller, Peter P.
, p. 4125 - 4128 (2007/10/02)
Synthesis of 4-phosphono(difluoromethyl)-D,L-phenylalanine as well as its diethyl phosphonate analogues bearing either Boc or Fmoc-amino protection are reported. The latter two derivatives were utilized for the solid-phase synthesis of SH2-related peptides containing nonhydrolyzable phosphotyrosyl mimetics.
