154287-22-6

Basic information

• Product Name: 1-<4-(3-chloropropoxy)phenyl>-2-phenyl-1-butanone
• Synonyms: 1-<4-(3-chloropropoxy)phenyl>-2-phenyl-1-butanone
• CAS NO: 154287-22-6
• Molecular Weight: 316.828
• Mol File: 154287-22-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-<4-(3-chloropropoxy)phenyl>-2-phenyl-1-butanone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-<4-(3-chloropropoxy)phenyl>-2-phenyl-1-butanone(154287-22-6)
• EPA Substance Registry System: 1-<4-(3-chloropropoxy)phenyl>-2-phenyl-1-butanone(154287-22-6)

Safety Data

• Hazardous Substances Data: 154287-22-6(Hazardous Substances Data)

Upstream product

• 3384-04-1 3-chloropropyl phenyl ether 
• 90-27-7 2-Phenylbutyric acid 

Downstream Products

• 154287-23-7 (E)-1-<4-(3-chloropropoxy)phenyl>-1-(4-iodophenyl)-2-phenyl-1-butene 

Relevant articles and documents

Substituted 1,1,2-triphenylbutenes and their use in the treatment of cancer

Compounds of the general formula (2) STR1 wherein n is an integer of from 3 to 10, the iodo substituent is in the 3- or 4-position and R 1 and R 2, which may be the same or different, represent C 1-3 alkyl, especially methyl or ethyl, groups or R l represents a hydrogen atom and R 2 a C 1-3 alkyl group or R 1 and R 2 together with the nitrogen atom to which they are attached represent a saturated heterocyclic group, especially a pyrrolidino group, in the form of their free bases or pharmaceutically acceptable acid addition salts are potent anti-oestrogenic compounds useful for treatment of oestrogen-dependent cancers, especially breast cancers. Compounds where the iodine atom is radioisotopic are useful in radiotherapy or gamma ray imaging of these cancers.