1542980-72-2

Upstream product

• 1542980-65-3 3-[(1S,2R,4R)-7-benzyloxycarbonyl-7-azabicyclo[2.2.1]heptane-2-carbonyl]-(4S)-[(1S)-methylpropyl]-2-oxazolidinone 
• 1542980-63-1 3-[(1S,2R,4R)-7-benzyloxycarbonyl-7-azabicyclo[2.2.1]heptane-2-carbonyl]-(4S)-(2-methylpropyl)-2-oxazolidinone 
• 1542980-57-3 3-[(1S,2R,4R)-7-Benzyloxycarbonyl-7-azabicyclo[2.2.1]heptane-2-carbonyl]-(4S)-methyl-2-oxazolidinone 
• 1542980-55-1 3-[(1S,2R,4R)-7-benzyloxycarbonyl-7-azabicyclo[2.2.1]heptane-2-carbonyl]-(4S)-[1-methylethyl]-2-oxazolidinone 

Relevant academic research and scientific papers

A facile synthesis of enantiopure 7-benzyloxycarbonyl-7-azabicyclo [2.2.1]heptane-2-carboxylic acid

An efficient procedure for the preparation of enantiopure 7-benzyloxycarbonyl-7-azabicyclo[2.2.1]heptane-2-carboxylic acids is described.

Synthesis of (-)-epibatidine

An asymmetric synthesis to the dendrobatid alkaloid (-)-epibatidine has been described, featuring chiral resolution of both optically pure 7-azabicyclo[2.2.1]heptanecarboxylic acid, and subsequent transformations to (-)-epibatidine. The methodology provides a flexible access to various substituted chiral epibatidine analogues.