154317-10-9

Basic information

• Product Name: 3-(3',5'-difluorobenzylidene)phthalide
• Synonyms: 3-(3',5'-difluorobenzylidene)phthalide
• CAS NO: 154317-10-9
• Molecular Weight: 258.224
• Mol File: 154317-10-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(3',5'-difluorobenzylidene)phthalide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(3',5'-difluorobenzylidene)phthalide(154317-10-9)
• EPA Substance Registry System: 3-(3',5'-difluorobenzylidene)phthalide(154317-10-9)

Safety Data

• Hazardous Substances Data: 154317-10-9(Hazardous Substances Data)

Upstream product

• 85-44-9 phthalic anhydride 
• 105184-38-1 3,5-difluorophenyl acetic acid 

Downstream Products

• 189634-60-4 3-(3',5'-difluorobenzylidene)(η6-phthalidetricarbonylchromium) 

Relevant articles and documents

Catalytic enantioselective synthesis of chiral phthalides by efficient reductive cyclization of 2-acylarylcarboxylates under aqueous transfer hydrogenation conditions

A new diamine ligand for asymmetric transfer hydrogenation (ATH) was discovered. The reductive cyclization of 2-acylarylcarboxylates was found to proceed highly stereoselective by the new Ru complex-catalyzed ATH and subsequent In situ lactonization under aqueous conditions. It enables efficient access to a wide variety of 3-substituted phthalides In enantiomerically pure form.