15433-03-1

Basic information

• Product Name: 2-(2,4,6-trimethylphenyl)-1H-indene-1,3(2H)-dione
• Synonyms: 1H-indene-1,3(2H)-dione, 2-(2,4,6-trimethylphenyl)-; 2-Mesityl-1H-indene-1,3(2H)-dione
• CAS NO: 15433-03-1
• Molecular Formula: C₁₈H₁₆O₂
• Molecular Weight: 264.3184
• Mol File: 15433-03-1.mol

Chemical Properties

• Boiling Point: 450°C at 760 mmHg
• Flash Point: 167.7°C
• Density: 1.177g/cm³
• Vapor Pressure: 2.73E-08mmHg at 25°C
• Refractive Index: 1.607
• CAS DataBase Reference: 2-(2,4,6-trimethylphenyl)-1H-indene-1,3(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2,4,6-trimethylphenyl)-1H-indene-1,3(2H)-dione(15433-03-1)
• EPA Substance Registry System: 2-(2,4,6-trimethylphenyl)-1H-indene-1,3(2H)-dione(15433-03-1)

Safety Data

• Hazardous Substances Data: 15433-03-1(Hazardous Substances Data)

Usage

Structure

2-(2,4,6-trimethylphenyl)-1H-indene-1,3(2H)-dione

Synonyms

Muskone

Appearance

Crystalline solid

Odor

Sweet, musky

Natural occurrence

Found in the musk glands of musk deer

Synthesis

Can be synthesized in the laboratory

Usage

Commonly used in perfumery, soaps, creams, and other personal care products

Fragrance properties

Unique and long-lasting scent

Fixative properties

Enhances and preserves the scent of other fragrances

Medical research

Studied for potential use as an anti-inflammatory and neuroprotective agent.

Upstream product

• 606-23-5 1H-indene-1,3(2H)-dione 
• 98740-62-6 2,2',4,4',6,6'-hexamethyl-diphenyliodonium chloride 
• 87-41-2 2-benzofuran-1(3H)-one 
• 487-68-3 mesytaldehyde 
• 108-67-8 1,3,5-trimethyl-benzene 
• 485-47-2 indan-1,2,3-trione hydrate 

Downstream Products

• 53082-95-4 C₁₉H₁₅ClO₃ 
• 53082-99-8 Carbonic acid bis-[3-oxo-2-(2,4,6-trimethyl-phenyl)-3H-inden-1-yl] ester 
• 53083-27-5 Dodecanoic acid 3-oxo-2-(2,4,6-trimethyl-phenyl)-3H-inden-1-yl ester 
• 53083-28-6 (E)-Undec-9-enoic acid 3-oxo-2-(2,4,6-trimethyl-phenyl)-3H-inden-1-yl ester 
• 53083-23-1 Methoxy-acetic acid 3-oxo-2-(2,4,6-trimethyl-phenyl)-3H-inden-1-yl ester 
• 53083-21-9 Methylsulfanyl-acetic acid 3-oxo-2-(2,4,6-trimethyl-phenyl)-3H-inden-1-yl ester 
• 53082-92-1 Carbonic acid 2-ethyl-hexyl ester 3-oxo-2-(2,4,6-trimethyl-phenyl)-3H-inden-1-yl ester 
• 53083-30-0 Carbonic acid dodecyl ester 3-oxo-2-(2,4,6-trimethyl-phenyl)-3H-inden-1-yl ester 
• 53083-41-3 Carbonic acid 4-chloro-phenyl ester 3-oxo-2-(2,4,6-trimethyl-phenyl)-3H-inden-1-yl ester 
• 53083-95-7 Propionic acid 3-oxo-2-(2,4,6-trimethyl-phenyl)-3H-inden-1-yl ester 
• 40580-62-9 2,2-Dimethyl-propionic acid 3-oxo-2-(2,4,6-trimethyl-phenyl)-3H-inden-1-yl ester 
• 41905-79-7 Acetic acid 3-oxo-2-(2,4,6-trimethyl-phenyl)-3H-inden-1-yl ester 
• 53083-01-5 2-Chloro-benzoic acid 3-oxo-2-(2,4,6-trimethyl-phenyl)-3H-inden-1-yl ester 
• 53083-00-4 Benzoic acid 3-oxo-2-(2,4,6-trimethyl-phenyl)-3H-inden-1-yl ester 

Relevant articles and documents

The reaction of ninhydrin with trimethylbenzenes under Friedel-Crafts reaction conditions

The reaction of ninhydrin with 1,2,3- and 1,2,4-trimethylbenzene in the presence of H2SO4 or AlCl3 afforded 2-monoaryl and 2,2-diaryl-1,3- indanedione derivatives as the major products. With 1,3,5-trimethylbenzene as the arene nucleophile, either a reduction product or an indenoindanone derivative was obtained depending upon the catalyst employed in the reaction.

Sterically Hindered Free Radicals. Part 22. Dimerization and EPR Spectroscopy of Indanedionyl and 9-Acylfluorenyl Radicals

2-Phenylindanedionyl radicals 5a, their p- and o-monosubstituted derivatives and related compounds 5b-h recombine by C-C bond formation giving 6a-h.In contrast, o-substituted derivatives 5i-k and the 2-tert-butylindanedionyl radicals 5l react to give the