154353-55-6Relevant articles and documents
Microwave-assisted rapid electrophilic fluorination of 1,3-dicarbonyl derivatives with Selectfluor
Xiao, Ji-Chang,Shreeve, Jean'ne M.
, p. 475 - 478 (2007/10/03)
A microwave-assisted fluorination method for 1,3-dicarbonyl compounds using Selectfluor has been developed. 2-Monofluorinated products can be obtained in high yield in neutral reaction conditions with addition of 1 eq. of Selectfluor. Treatment of 1,3-dicarbonyls with 3 eq. of Selectfluor in the presence of tetrabutylammonium hydroxide (TBAH) as the base results in the formation of 2,2-difluorinated derivatives only.