154367-52-9 Usage
Explanation
The molecular formula represents the number of atoms of each element present in a molecule. In this case, the compound has 5 carbon atoms, 6 hydrogen atoms, 1 chlorine atom, 1 nitrogen atom, and 1 oxygen atom.
Explanation
The IUPAC name is a systematic method of naming chemical compounds, ensuring that each compound has a unique and unambiguous name.
Explanation
Synonyms are alternative names for a compound, often used interchangeably. In this case, the compound is also known as 2,3-dihydro-1H-pyrrolizin-2-one.
Explanation
The compound has a ring structure consisting of five atoms, with at least one atom in the ring being a different element than carbon (in this case, nitrogen).
5. Presence of Chlorine and Nitrogen atoms
Explanation
The compound contains a chlorine atom and a nitrogen atom within its five-membered ring structure, contributing to its unique chemical properties.
Explanation
Due to its versatile reactivity and ability to form diverse chemical bonds, 1-Chloro-1,2-dihydro-3H-pyrrolizin-3-one is used as a building block in the synthesis of pharmaceuticals and agrochemicals.
Explanation
The compound has been studied for its potential antimicrobial and anti-inflammatory properties, which could lead to its use in the development of new drugs or treatments.
Explanation
1-Chloro-1,2-dihydro-3H-pyrrolizin-3-one is utilized as an intermediate in organic synthesis, meaning it is a compound that is used to produce other compounds through chemical reactions.
Explanation
The compound can be produced through various chemical reactions, making it a valuable compound in the field of organic chemistry due to its synthetic versatility.
Synonyms
2,3-dihydro-1H-pyrrolizin-2-one
Chemical Structure
Heterocyclic compound with a five-membered ring
Pharmaceutical and Agrochemical Applications
Building block in synthesis
Antimicrobial and Anti-inflammatory Properties
Potential applications
Organic Synthesis
Intermediate compound
Production
Various chemical reactions
Check Digit Verification of cas no
The CAS Registry Mumber 154367-52-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,3,6 and 7 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 154367-52:
(8*1)+(7*5)+(6*4)+(5*3)+(4*6)+(3*7)+(2*5)+(1*2)=139
139 % 10 = 9
So 154367-52-9 is a valid CAS Registry Number.
154367-52-9Relevant academic research and scientific papers
McNab, Hamish,Thornley, Craig
, p. 1570 - 1571 (1993)
1-Substituted 1,2-dihydropyrrolizin-3-ones can be obtained from pyrrolizin-3-one 2 by conjugate nucleophilic addition or electrophilic addition reactions; the 1-chloro compound 9 obtained by the latter method is used as a key intermediate in a six-step synthesis of the title compound 3 from 4-acetoxymethylpyridine-N-oxide.
Chemistry of pyrrolizinones. Part 1. Reactions of pyrrolizin-3-ones with electrophiles: Synthesis of 3,8-didehydroheliotridin-5-one
McNab, Hamish,Thornley, Craig
, p. 3584 - 3591 (2007/10/03)
The reaction of pyrrolizin-3-one 1 with dry hydrogen chloride gives the 1-chloro-1,2-dihydro derivative 8 (93%) by electrophilic addition. The halogen of 8 is readily displaced by O-nucleophiles to give 6, 9 or 10 in 87-100% yield, and this strategy has been employed in a short synthesis of the necine base didehydroheliotridin-5-one 4. Pyrrolizinone 1 can be brominated by N-bromosuccinimide in the presence of nucleophiles to give 20 or 21, or under free radical conditions to give the 2-bromopyrrolizinone 22 (55%). Vilsmeier formylation of 1 gave a variety of products including the 5-formylpyrrolizinone 26 (16%), but azo-coupling could only be observed under basic conditions to give the coupled propenoate 31 (46%) via the anion of the ring-opened species 30. The Royal Society of Chemistry 2000.
