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2-hydroxy-1-imidazol-1-yl-2,2-diphenyl-ethanone, commonly known as diphenidol, is a chemical compound that features an imidazole ring fused with a diphenylethanone group. This unique structure endows diphenidol with potential pharmaceutical applications, making it a compound of interest in the medical field.

15441-11-9

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15441-11-9 Usage

Uses

Used in Pharmaceutical Industry:
Diphenidol is used as an antiemetic agent for controlling nausea and vomiting, providing relief to patients suffering from these symptoms.
It is used as a treatment for motion sickness and vertigo, helping to alleviate the discomfort and disorientation associated with these conditions.
Diphenidol is also being investigated for its potential to treat Meniere's disease, a disorder affecting the inner ear that can lead to vertigo, tinnitus, and hearing loss, offering a possible therapeutic intervention for those affected by this condition.

Check Digit Verification of cas no

The CAS Registry Mumber 15441-11-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,4,4 and 1 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 15441-11:
(7*1)+(6*5)+(5*4)+(4*4)+(3*1)+(2*1)+(1*1)=79
79 % 10 = 9
So 15441-11-9 is a valid CAS Registry Number.

15441-11-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-hydroxy-1-imidazol-1-yl-2,2-diphenylethanone

1.2 Other means of identification

Product number -
Other names 1-(hydroxy-diphenyl-acetyl)-1H-imidazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15441-11-9 SDS

15441-11-9Relevant academic research and scientific papers

Method For Producing Azoniaspironortropine Esters And Nortropan-3-One Compounds

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Page/Page column 11, (2010/03/31)

The present technology relates to an improved one-stage method for producing azoniaspironortropine esters such as trospium chloride by reacting an endonortropine compound with an organic dihalogen compound and an a-hydroxycarboxylic acid in the presence of a base and 1,1′ carbonyldiimidazole or 1,1′ thiocarbonyldiimidazole or thionyldiimidazole. The present technology also relates to an improved method for producing nortropan-3-one compounds or their hydrohalides (such as N-benzyltropanone hydrochloride) by reacting an amine and a protected dialdehyde with a basic aqueous solution of 1,3-acetone dicarboxylic acid.

Synthesis of the bronchospasmolytic agent flutropium bromide and of some homologous and configuration isomeric compounds

Banholzer,Pook,Stiasni

, p. 1161 - 1166 (2007/10/02)

A technically practicable synthesis of unknown N-β-fluoroalkyl-substituted benzilic acid nortropine esters, among them (8r)-8-(2-fluoroethyl)-3α-hydroxy-1αH,5αH-tropanium bromide benzilic acid ester (flutropium bromide, Ba 598 BR), and their configuration isomeric quaternary salts via benzilic acid imidazolide is described. The quaternization which takes place with sufficiently high stereoselectivity leads to configuration isomers which differ not only in their physico-chemical properties but also in their profile of pharmacological action.

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