15441-45-9Relevant academic research and scientific papers
Biosynthesis of tetraponerine-6. Evidence that two different pathways are operating in the biosynthesis of the two tetraponerine skeletons
Devijver,Braekman,Daloze,Pasteels
, p. 661 - 662 (1997)
Evidence is presented showing that tetraponerine-6 2a from Tetraponera sp. ants is biosynthesized from two molecules of putrescine and a seven-carbon moiety coming from an eight-carbon polyacetate chain through decarboxylation, in contrast with tetraponerine-8 1a, which derives from one putrescine unit and a twelve-carbon polyacetate precursor.
Biosynthesis of tetraponerine-8, a defence alkaloid of the ant Tetraponera sp.
Renson, B.,Merlin, P.,Daloze, D.,Braekman, J. C.,Roisin, Y.,Pasteels, J. M.
, p. 105 - 109 (2007/10/02)
The administration of sodium and acetate, L- glutamic acid, γ-amino butyric acid, L- ornithine hydrochloride, and putrescine dihydrochloride to Tetraponera sp. ants resulted in the formation, for each feeding experiment, of labelled tetraponerine-8 (2).The distribution of radioactivity into 2 was established by chemical degradation.The results obtained favor the hypothesis that the pyrrolidine ring of tetraponerine-8 is derived from L-glutamic acid via L-ornithine and putrescine, while the 12-carbon chain is derived from the combination of six acetate units.
