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(D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7,β-(3-pyridyl)-D-Ala9,Nle11)-Substance P is a neuropeptide derivative with a unique arrangement of amino acid residues, including D-lysine, nicotinoyl, beta-(3-pyridyl)-alanine, 3,3,4-dichloro-D-phenylalanine, asparagine, D-tryptophan, beta-(3-pyridyl)-D-alanine, and norleucine. (D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7,β-(3-pyridyl)-D-Ala9,Nle11)-Substance P is designed to modulate the biological activity of Substance P, which plays a role in pain perception and inflammation.

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  • (D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7,β-(3-pyridyl)-D-Ala9,Nle11)-Substance P

    Cas No: 154427-06-2

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  • (D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7,β-(3-pyridyl)-D-Ala9,Nle11)-Substance P

    Cas No: 154427-06-2

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  • L-Norleucinamide,N6-(3-pyridinylcarbonyl)-D-lysyl-L-prolyl-3-(3-pyridinyl)-L-alanyl-L-prolyl-3,4-dichloro-D-phenylalanyl-L-asparaginyl-D-tryptophyl-L-phenylalanyl-3-(3-pyridinyl)-D-alanyl-L-leucyl-

    Cas No: 154427-06-2

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  • (D-Lys(nicotinoyl)1,-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7,-(3-pyridyl)-D-Ala9,Nle11)-Substance P

    Cas No: 154427-06-2

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  • 154427-06-2 Structure
  • Basic information

    1. Product Name: (D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7,β-(3-pyridyl)-D-Ala9,Nle11)-Substance P
    2. Synonyms: (D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7,β-(3-pyridyl)-D-Ala9,Nle11)-Substance P;(D-Lys(nicotinoyl)1,b-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7,b-(3-pyridyl)-D-Ala9,Nle11)-Substance P;H-D-Lys(nicotinoyl)-Pro-b-(3-pyridyl)-Ala-Pro-3,4-dichloro-D-Phe-Asn-D-Trp-Phe-b-(3-pyridyl)-D-Ala-Leu-Nle-NH2
    3. CAS NO:154427-06-2
    4. Molecular Formula: C83H102Cl2N18O13
    5. Molecular Weight: 1630.71678
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 154427-06-2.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.321±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. PKA: 13.03±0.46(Predicted)
    10. CAS DataBase Reference: (D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7,β-(3-pyridyl)-D-Ala9,Nle11)-Substance P(CAS DataBase Reference)
    11. NIST Chemistry Reference: (D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7,β-(3-pyridyl)-D-Ala9,Nle11)-Substance P(154427-06-2)
    12. EPA Substance Registry System: (D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7,β-(3-pyridyl)-D-Ala9,Nle11)-Substance P(154427-06-2)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 154427-06-2(Hazardous Substances Data)

154427-06-2 Usage

Uses

Used in Pharmaceutical Industry:
(D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7,β-(3-pyridyl)-D-Ala9,Nle11)-Substance P is used as a potential therapeutic agent for conditions related to pain and inflammation. Its unique structure allows it to modulate the biological activity of Substance P, which is involved in these processes.
Used in Research Applications:
In the field of neuroscience and pharmacology, (D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7,β-(3-pyridyl)-D-Ala9,Nle11)-Substance P can be used as a research tool to study the mechanisms of pain perception and inflammation, as well as to develop new drugs targeting these pathways.
Used in Drug Development:
The specific arrangement of amino acids in (D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7,β-(3-pyridyl)-D-Ala9,Nle11)-Substance P may confer unique pharmacological properties that could be exploited in the development of new drugs for the treatment of pain and inflammation-related conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 154427-06-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,4,2 and 7 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 154427-06:
(8*1)+(7*5)+(6*4)+(5*4)+(4*2)+(3*7)+(2*0)+(1*6)=122
122 % 10 = 2
So 154427-06-2 is a valid CAS Registry Number.

154427-06-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name (D-Lys(nicotinoyl)1,β-(3-pyridyl)-Ala3,3,4-dichloro-D-Phe5,Asn6,D-Trp7,β-(3-pyridyl)-D-Ala9,Nle11)-Substance P

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:154427-06-2 SDS

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