1544274-17-0

Basic information

• Product Name: 5-(4-bromophenyl)-3-methyl-6-phenyl-7-thioxo-1,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidine-2,4-dione
• Synonyms: 5-(4-bromophenyl)-3-methyl-6-phenyl-7-thioxo-1,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidine-2,4-dione
• CAS NO: 1544274-17-0
• Molecular Weight: 443.324
• Mol File: 1544274-17-0.mol

Chemical Properties

• CAS DataBase Reference: 5-(4-bromophenyl)-3-methyl-6-phenyl-7-thioxo-1,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-bromophenyl)-3-methyl-6-phenyl-7-thioxo-1,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidine-2,4-dione(1544274-17-0)
• EPA Substance Registry System: 5-(4-bromophenyl)-3-methyl-6-phenyl-7-thioxo-1,3,5,6,7,8-hexahydropyrimido[4,5-d]pyrimidine-2,4-dione(1544274-17-0)

Safety Data

• Hazardous Substances Data: 1544274-17-0(Hazardous Substances Data)

Upstream product

• 21236-97-5 3-methyl-6-aminouracil 
• 103-72-0 phenyl isothiocyanate 
• 1122-91-4 4-bromo-benzaldehyde 

Relevant articles and documents

An efficient and regioselective one-pot multi-component synthesis of pyrimido[4,5-d]pyrimidine derivatives in water

Pyrimido[4,5-d]pyrimidine derivatives 4 have been prepared in an efficient and regioselective manner in water via multi-component reaction of isothiocyanate 1, aromatic aldehyde 2, N,N-dimethyl-6-amino uracil 3 in the presence of p-toluenesulfonic acid (p-TSA) as a Lewis acid catalyst.