154445-77-9

Basic information

• Product Name: FMOC-Arg(Pbf)-OH
• Synonyms: na-fmoc-ng-(2,2,4,6,7-pentamethyl-*dihydrobenzofu;FMOC-N-OMEGA-(2,2,4,6,7-PENTAMETHYLDIHYDROBENZOFURAN-5-SULFONYL)-L-ARGININE;FMOC-NG-PBF-L-ARGININE;FMOC-ARG(PBF);FMOC-ARGININE(PBF)-OH;FMOC-ARG(PBF)-OH;FMOC-(2,2,4,6,7-PENTAMETHYLDIHYDROBENZOFURAN-5-SULFONYL)-L-ARGININE;FMOC-L-ARGININE(PBF)
• CAS NO: 154445-77-9
• Molecular Formula: C₃₄H₄₀N₄O₇S
• Molecular Weight: 648.77
• EINECS: 1592732-453-0
• Product Categories: Amino Acids;Arginine [Arg, R];Fmoc-Amino Acids and Derivatives;Fmoc-Amino acid series
• Mol File: 154445-77-9.mol
• Article Data: 0

Chemical Properties

• Melting Point: 132°C
• Appearance: White or off-white powder
• Density: 1.37 g/cm³
• Refractive Index: 1.648
• Storage Temp.: −20°C
• Solubility: DMF (Sparingly), DMSO (Slightly), Methanol (Slightly)
• PKA: 3.83±0.21(Predicted)
• BRN: 8302671
• CAS DataBase Reference: FMOC-Arg(Pbf)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: FMOC-Arg(Pbf)-OH(154445-77-9)
• EPA Substance Registry System: FMOC-Arg(Pbf)-OH(154445-77-9)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 1
• HazardClass: IRRITANT
• Hazardous Substances Data: 154445-77-9(Hazardous Substances Data)

Usage

Chemical Properties

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Uses

Different sources of media describe the Uses of 154445-77-9 differently. You can refer to the following data:
1. Fmoc-Arg(Pbf)-OH, is an amino acid building block used in peptide synthesis. With a growing peptide drug market the fast, reliable synthesis of peptides is of great importance.
2. Fmoc-Arg(Pbf)-OH is a Fmoc-protected amino acid derivative that can be used to create arginine-containing peptides. The 2,2,4,6,7-pentamethyIdlhydrobenzofuran-5-sulfonyl group (Pbf) can be easily cleaved by trifluoroacetic acid (TFA).

InChI:InChI=1/C34H40N4O7S/c1-19-20(2)30(21(3)29-26(19)17-34(4,5)45-29)46(42,43)38-32(35)36-16-10-15-28(31(39)40)37-33(41)44-18-27-24-13-8-6-11-22(24)23-12-7-9-14-25(23)27/h6-9,11-14,27-28H,10,15-18H2,1-5H3,(H,37,41)(H,39,40)(H3,35,36,38)/t28-/m1/s1

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