154445-78-0 Usage
Chemical Properties
White to gray powder
Uses
reagent for introducing the PBF protection in arginine’s guanidine group
Check Digit Verification of cas no
The CAS Registry Mumber 154445-78-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,4,4 and 5 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 154445-78:
(8*1)+(7*5)+(6*4)+(5*4)+(4*4)+(3*5)+(2*7)+(1*8)=140
140 % 10 = 0
So 154445-78-0 is a valid CAS Registry Number.
InChI:InChI=1/C13H17ClO3S/c1-7-8(2)12(18(14,15)16)9(3)10-6-13(4,5)17-11(7)10/h6H2,1-5H3
154445-78-0Relevant articles and documents
The 2,2,4,6,7-Pentamethyldihydrobenzofuran-5-sulfonyl Group (Pbf) as Arginine Side Chain Protectant
Carpino, Louis A.,Shroff, Hitesh,Triolo, Salvatore A.,Mansour, El-Sayed M. E.,Wenschuh, Holger,Albericio, Fernando
, p. 7829 - 7832 (1993)
The 2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl residue (Pbf) is more easily deblocked by trifluoroacetic acid (TFA) than the corresponding Pmc analog and can be used efficiently in the synthesis of arginine-containing peptides.