154458-46-5Relevant academic research and scientific papers
ASYMMETRIC SYNTHESIS OF THE ANTICOCCIDIAL ANTIBIOTIC DIOLMYCIN A1. DETERMINATION OF ABSOLUTE STEREOCHEMISTRY
Sunazuka, Toshiaki,Tabata, Noriko,Nagamitsu, Tohru,Tomoda, Hiroshi,Omura, Satoshi,Smith, Amos B.
, p. 6659 - 6660 (2007/10/02)
An asymmetric total synthesis of diolmycin A1 (1), a recently discovered anticoccidial antibiotic, has been achieved in six steps from 2-(4-hydroxyphenyl)ethanol.The natural product comprises an unusual ca. 4:1 mixture of enantiomers; the synthesis defined the (11R,12S) absolute configuration of the predominant (-) antipode.
