154470-72-1Relevant academic research and scientific papers
Rearrangement of 2,3-dioxo-1,4-oxazines to 4,5-dioxooxazoles in the reaction with dimethylsulfoxonium methylide
Toda,Seki,Amano,Oyama,Sano,Kiuchi,Tsuda
, p. 739 - 741 (1994)
Reaction of 2,3-dioxo-2,3-dihydro-4H-1,4-oxazines 2a-e with dimethylsulfoxonium methylide introduced an exomethylene group with concomitant ring contraction to give 4,5-dioxo-2,3,4,5-tetrahydrooxazoles 3a- e in moderate yields. Mechanism of this unusual r
OXIDATION OF DIOXOPYRROLINE WITH M-CHLOROPERBENZOIC ACID: SELECTIVE FORMATION OF 2,3-DIOXO-1,4-OXAZINE
Sano, Takehiro,Amano, Kazuko,Seki, Masaharu,Hirota, Hiroyuki,Toda, Jun,et al.
, p. 523 - 528 (2007/10/02)
Treatment of 4-ethoxycarbonyl-5-phenyl-1H-pyrrole-2,3-diones (1a-1e) and 4-benzoyl-1,5-diphenyl-1H-pyrrole-2,3-dione (1f) with m-chloroperbenzoic acid caused Bayer-Villiger oxidation to give 2,3-dioxo-1,4-oxazines (2a-2f) in modrate yields, respectively.This conversion of the 1H-pyrrole-2,3-dione into the 2,3-dioxo-1,4-oxazine provides the first synthesis of monocyclic 2,3-dioxo-1,4-oxazine ring system.
