1544739-77-6

Basic information

• Product Name: (5aR,6S,6aS)-ethyl 3-((2’,6’-dimethyl-4’-(3-(methylsulfonyl)propoxy)-[1,1‘-biphenyl]-3-yl)methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylate
• Synonyms: (5aR,6S,6aS)-ethyl 3-((2’,6’-dimethyl-4’-(3-(methylsulfonyl)propoxy)-[1,1‘-biphenyl]-3-yl)methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylate
• CAS NO: 1544739-77-6
• Molecular Weight: 549.688
• Mol File: 1544739-77-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (5aR,6S,6aS)-ethyl 3-((2’,6’-dimethyl-4’-(3-(methylsulfonyl)propoxy)-[1,1‘-biphenyl]-3-yl)methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: (5aR,6S,6aS)-ethyl 3-((2’,6’-dimethyl-4’-(3-(methylsulfonyl)propoxy)-[1,1‘-biphenyl]-3-yl)methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylate(1544739-77-6)
• EPA Substance Registry System: (5aR,6S,6aS)-ethyl 3-((2’,6’-dimethyl-4’-(3-(methylsulfonyl)propoxy)-[1,1‘-biphenyl]-3-yl)methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylate(1544739-77-6)

Safety Data

• Hazardous Substances Data: 1544739-77-6(Hazardous Substances Data)

Upstream product

• 1544739-10-7 (4-bromo-5-vinyl-pyridin-2-yl)-bis-(4-methoxy-benzyl)-amine 
• 1544739-11-8 (4-allyl-5-vinyl-pyridin-2-yl)-bis-(4-methoxy-benzyl)-amine 
• 1544739-12-9 bis-(4-methoxy-benzyl)-(5H-[2]pyrindin-3-yl)-amine 
• 1544739-13-0 4-[bis-(4-methoxy-benzyl)-amino]-1,1a,6,6a-tetrahydro-3-aza-cyclopropa[a]-indene-1-carboxylic acid ethyl ester 
• 1544739-15-2 4-amino-1,1a,6,6a-tetrahydro-3-aza-cyclopropa[a]indene-1-carboxylic acid ethyl ester 
• 1544739-07-2 4-hydroxy-1,1a,6,6a-tetrahydro-3-aza-cyclopropa[a]indene-1-carboxylic acid ethyl ester 
• 84249-14-9 2-amino-4-bromopyridine 
• 1544739-08-3 (4-bromo-pyridin-2-yl)-bis-(4-methoxy-benzyl)-amine 
• 1544739-09-4 (4-bromo-5-iodo-pyridin-2-yl)-bis-(4-methoxy-benzyl)-amine 
• 1372195-69-1 2-bromo-5-(3-methanesulfonyl-propoxy)-1,3-dimethyl-benzene 
• 443776-76-9 (3‐(4,4,5,5‐tetramethyl‐1,3,2‐dioxaborolan‐2‐yl)phenyl)methanol 
• 1000413-85-3 (2’,6’-dimethyl-4’-(3-(methylsulfonyl)propoxy)-[1,1‘-biphenyl]-3-yl)methanol 
• 1372194-98-3 3‘-(bromomethyl)-2,6-dimethyl-4-(3-(methylsulfonyl)propoxy)-1,1‘-biphenyl 
• 1544739-23-2 ethyl 3-hydroxy-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylate 

Downstream Products

• 1544739-75-4 (5aR,6S,6aS)-ethyl 3-((2’,6’-dimethyl-4’-(3-(methylsulfonyl)propoxy)-[1,1‘-biphenyl]-3-yl)methoxy)-5,5a,6,6a-tetrahydrocyclopropa[4,5]cyclopenta[1,2-c]pyridine-6-carboxylic acid 

Relevant articles and documents

ANTIDIABETIC TRICYCLIC COMPOUNDS

Novel compounds of the structural formula (I), and the pharmaceutically acceptable salts thereof, are agonists of G-protein coupled receptor 40 (GPR40) and may be useful in the treatment, prevention and suppression of diseases mediated by the G-protein-coupled receptor 40. The compounds of the present invention may be useful in the treatment of Type 2 diabetes mellitus, and of conditions that are often associated with this disease, including obesity and lipid disorders, such as mixed or diabetic dyslipidemia, hyperlipidemia, hypercholesterolemia, and hypertriglyceridemia.