154520-17-9Relevant academic research and scientific papers
A new approach to the stereoselective synthesis of conveniently protected α-allyl substituted amino acids; chiral key compounds in the synthesis of constrained peptide isostere constituents
Badorrey, Ramon,Cativiela, Carlos,Diaz-de-Villegas, Maria D.,Galvez, Jose A.,Lapena, Yolanda
, p. 311 - 317 (2007/10/03)
Enantiomerically pure α-allyl-N-Boc-aminoamides were prepared by Curtius rearrangement of α,α-dialkyl chiral 2-cyanoesters obtained by the diastereoselective allylation of chiral 2-cyanoesters according to a modification of our previously described proced
Asymmetric Synthesis of β-Lactams. Highly Diastereoselective Alkylation of Chiral 2-Cyano Esters
Cativiela, Carlos,Diaz-de-Villegas, Maria D.,Galvez, Jose A.
, p. 2497 - 2505 (2007/10/02)
Enolates derived from 10-(dicyclohexylsulfamoyl)isobornyl 2-substituted-2-cyanoacetates were alkylated with very good yield and high diastereoselectivity.The reduction of the resulting reaction products and subsequent cyclization of the β-amino acids led
