154520-47-5Relevant academic research and scientific papers
SINTESIS ASIMETRICA DE α-FENILAMINOACIDOS
Cativiela, Carlos,Villegas, Maria D. Diaz de,Galvez, Jose A.,Lapena, Yolanda
, p. 432 - 437 (2007/10/02)
A new synthetic strategy to obtain α-phenylamino acids in enantiomerically pure form is described.The new route is based on the highly diastereoselective alkylation of (1S,2R,4R)-10-dicyclohexylsulfamoylisobornyl 2-phenylcyanoacetate and subsequent Curtiu
Asymmetric Synthesis of β-Lactams. Highly Diastereoselective Alkylation of Chiral 2-Cyano Esters
Cativiela, Carlos,Diaz-de-Villegas, Maria D.,Galvez, Jose A.
, p. 2497 - 2505 (2007/10/02)
Enolates derived from 10-(dicyclohexylsulfamoyl)isobornyl 2-substituted-2-cyanoacetates were alkylated with very good yield and high diastereoselectivity.The reduction of the resulting reaction products and subsequent cyclization of the β-amino acids led
