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Usage

Uses

Used in Cosmetic and Personal Care Industry:
Cholesteryl hexadecyl carbonate is used as an emollient and skin conditioning agent for its ability to create a protective barrier on the skin, helping to retain moisture and prevent dehydration. This contributes to improved skin hydration and overall appearance.
Used in Skincare Products:
Cholesteryl hexadecyl carbonate is used as an antioxidant in skincare products to potentially protect the skin from damage caused by free radicals, thus promoting healthier and more resilient skin.

InChI:InChI=1/C44H78O3/c1-7-8-9-10-11-12-13-14-15-16-17-18-19-20-32-46-42(45)47-37-28-30-43(5)36(33-37)24-25-38-40-27-26-39(35(4)23-21-22-34(2)3)44(40,6)31-29-41(38)43/h24,34-35,37-41H,7-23,25-33H2,1-6H3/t35-,37+,38+,39-,40+,41+,43+,44-/m1/s1

Upstream product

• 36653-82-4 1-Hexadecanol 
• 7144-08-3 Cholesteryl chloroformate 

Relevant academic research and scientific papers

Physicochemical properties and antifungal activity of amphotericin b incorporated in cholesteryl carbonate esters

The antifungal activity of amphotericin B (AmB) incorporated in three cholesteryl carbonate esters (CCEs), sodium cholesteryl carbonate, cholesteryl palmityl carbonate, and dicholesteryl carbonate, was examined to assess their potential for use in a dry powder aerosol. Formulations containing dissolved AmB were stable for 6 months. The particle size varied inversely with liquid crystalline content with observed mass median aerodynamic diameters ranging from 4 to 8 μm. This was consistent with the visual appearance of the liquid crystals as being low density and free flowing at room temperature. When dispersed in water, the presence of the CCE reduced the rate and extent of AmB release, consistent with the estimated liquid crystal/water partition coefficient. Nevertheless, the rate of AmB release was always sufficient to kill the fungus as established with bioactivity studies. AmB formulated with CCE as a dry powder appears to be promising for use in treating lung fungal infections.