154550-06-8

Upstream product

• 83-40-9 3-methylsalicylic acid 
• 106-95-6 allyl bromide 

Downstream Products

• 145526-82-5 2-(allyloxy)-3-methylbenzoic acid 
• 1412443-87-8 C₃₃H₆₁NO₄Si₂ 
• 1412443-81-2 2-(allyloxy)-N,N-diisopropyl-3-methylbenzamide 
• 1412443-86-7 2-(allyloxy)-6-((5S,6R)-8,8-diethyl-2,2,3,3-tetramethyl-6-((R)-pent-4-en-2-yl)-4,7-dioxa-3,8-disiladecan-5-yl)-N,N-diisopropyl-3-methylbenzamide 
• 1412443-75-4 2-(allyloxy)-6-((1S,2R,3R)-1-hydroxy-3-methyl-2-(triethylsilyloxy)hex-5-enyl)-N,Ndiisopropyl-3-methylbenzamide 
• 153034-30-1 (2-(allyloxy)-3-methylphenyl)methanol 
• 153034-23-2 2-(allyloxy)-3-methylbenzaldehyde 
• 1207288-87-6 3-(2-(allyloxy)-3-methylphenyl)propiolic acid 
• 1207288-86-5 methyl 3-(2-(allyloxy)-3-methylphenyl)propiolate 
• 1207288-85-4 2-(allyloxy)-1-(2,2-dibromovinyl)-3-methylbenzene 
• 154550-02-4 methyl 2-allyloxy-3-methylbenzoate 
• 23287-26-5 3-methylsalicylic acid methyl ester 

Relevant academic research and scientific papers

Total Synthesis of Ajudazol A by a Modular Oxazole Diversification Strategy

The total synthesis of the potent respiratory chain inhibitor ajudazol A was accomplished by a concise strategy in 17 steps (longest linear sequence). The modular approach was based on a direct oxazole functionalization strategy involving a halogen dance

Stereoselective Synthesis of Isochromanones by an Asymmetric Ortho-Lithiation Strategy: Synthetic Access to the Isochromanone Core of the Ajudazols

Full details on the design, development, and application of a highly stereoselective strategy for the synthesis of isochromanones are reported. The method is based on an asymmetric ortho lithiation with aldehyde electrophiles and utilizes the chiral memor

Full stereochemical determination of ajudazols a and b by bioinformatics gene cluster analysis and total synthesis of ajudazol B by an asymmetric ortholithiation strategy

The stereochemical determination of the potent respiratory chain inhibitors ajudazols A and B and the total synthesis of ajudazol B are reported. Configurational assignment was exclusively based on biosynthetic gene cluster analysis of both ketoreductase

Palladium-catalyzed intramolecular carboesterification of olefins

One catalyst three bonds: The title reaction between propiolic acids and unactivated olefins (see scheme; O red, Cl green) results in vicinal functionalization of the olefin, with the formation of new C-C and C-O bonds. Structurally complex 6,7,5-tricyclic ring systems are formed in a single step by this cascade chloropalladation and formal [3+2] cycloaddition.

Pyrolysis of O-Allyl Salicylic Amides and Esters, and Related Compounds: Foemation of Isoindolones and Phthalides

Flash vacuum pyrolysis of O-allyl salicylic alkylamides and alkyl esters gives isoindolones and phthalides, respectively, in low (20-40percent) yield.The mechanism involves generation of the phenoxyl radical, regiospecific hydrogen-atom transfer from the alkylamide (or alkyl ester) group and cyclization.A similar sequence was observed with thiophenoxyl radicals.