154557-48-9Relevant academic research and scientific papers
Stereochemical features of oxidative Mannich cyclizations of vinyl- and allyl-silane containing α-silyl-amines and -amides
Khim, Seock-Kyu,Wu, Xiaodong,Mariano, Patrick S.
, p. 571 - 574 (2007/10/02)
Studies of the new oxidative Mannich cyclization reaction of α-silyl-amines and -amides demonstrate advantageous features of the process when applied to stereocontrolled hydropyridine syntheses.
SET-photosensitized reactions of α-silylamino-enones and ynones proceeding by 6-endo α-amino radical cyclization pathways
Khim, Seock-Kyu,Cederstrom, Ericka,Ferri, Dino C.,Mariano, Patrick S.
, p. 3195 - 3222 (2007/10/03)
SET-photosensitized reactions of α,β-enones and -ynones containing tethered α-silylamine functions are described. The processes lead to hydropyridine ring construction via pathways involving 6-endo type α-amino radical cyclizations. High degrees of regio- and stereocontrol attend these reactions.
