154578-23-1 Usage
General Description
Imidazo[1,2-b]pyridazine, 6-chloro-2-(chloromethyl)- is a chemical compound with a heterocyclic ring structure containing both an imidazole and pyridazine ring. It has a chlorine atom at the 6th position on the pyridazine ring, and a chloromethyl group attached to the 2nd position. Imidazo[1,2-b]pyridazine, 6-chloro-2-(chloromethyl)- is a potential intermediate in the synthesis of pharmaceuticals and agrochemicals. It may also have applications in materials science and organic synthesis. The specific properties and uses of this compound may depend on its particular chemical structure and functional groups.
Check Digit Verification of cas no
The CAS Registry Mumber 154578-23-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,5,7 and 8 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 154578-23:
(8*1)+(7*5)+(6*4)+(5*5)+(4*7)+(3*8)+(2*2)+(1*3)=151
151 % 10 = 1
So 154578-23-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H5Cl2N3/c8-3-5-4-12-7(10-5)2-1-6(9)11-12/h1-2,4H,3H2
154578-23-1Relevant articles and documents
Synthesis of 2-substituted-3-nitroimidazo[1,2-b]pyridazines as potential biologically active agents
Terme, Thierry,Galtier, Christophe,Maldonado, Jose,Crozet, Michel P.,Gueiffier, Alain,Vanelle, Patrice
, p. 173 - 177 (2002)
A new heterocyclic reductive alkylating agent, 6-chloro-2-chloromethyl-3-nitroimidazo[1,2-b]pyridazine, was synthesized for the first time. It was shown to react under phase-transfer catalysis conditions with 2-nitropropane anion by an SRN1 mechanism to give excellent yield of isopropylidene derivative formed from a base-promoted nitrous acid elimination of C-alkylation product. Extension of this SRN1 reaction to various nitronate anions led to a new class of 3-nitroimidazo[1,2-b]pyridazine derivatives bearing a trisubstituted double bond at the 2-position.
