154578-26-4 Usage
General Description
6-Chloro-imidazo[1,2-b]pyridazine-3-carboxaldehyde is a chemical compound with the molecular formula C8H5ClN4O. 6-CHLORO-IMIDAZO[1,2-B]PYRIDAZINE-3-CARBOXALDEHYDE contains a heterocyclic ring system and a chlorine atom, and it is classified as an aldehyde. It is used as an intermediate in the synthesis of pharmaceutical compounds, agrochemicals, and other organic compounds. The presence of the imidazo[1,2-b]pyridazine ring structure in this compound makes it potentially useful in medicinal chemistry for the development of new drugs. Its aldehyde functional group also makes it a versatile building block for the construction of more complex organic molecules. Overall, 6-Chloro-imidazo[1,2-b]pyridazine-3-carboxaldehyde has various applications in the field of organic synthesis and pharmaceutical research.
Check Digit Verification of cas no
The CAS Registry Mumber 154578-26-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,4,5,7 and 8 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 154578-26:
(8*1)+(7*5)+(6*4)+(5*5)+(4*7)+(3*8)+(2*2)+(1*6)=154
154 % 10 = 4
So 154578-26-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H4ClN3O/c8-6-1-2-7-9-3-5(4-12)11(7)10-6/h1-4H
154578-26-4Relevant articles and documents
HETEROCYCLIC HYDRAZONE COMPOUNDS AND THEIR USES TO TREAT CANCER AND INFLAMMATION
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Page/Page column 55-56, (2011/02/24)
The invention relates to compounds of formula (I) and salts thereof: wherein the substituents are as defined in the specification; a compound of formula (I) for use in the treatment of the human or animal body, in particular with regard to c-Met tyrosine kinase mediated diseases or conditions; the use of a compound of formula (I) for manufacturing a medicament for the treatment of such diseases; pharmaceutical compositions comprising a compound of the formula (I), optionally in the presence of a combination partner, and processes for the preparation of a compound of formula (I).
Efficient preparation of imidazo[1,2-b]pyridazines under Swern oxidative conditions
Raboisson, Pierre,Mekonnen, Belew,Peet, Norton P.
, p. 2919 - 2921 (2007/10/03)
An efficient synthesis of new imidazo[1,2-b]pyridazine derivatives was effected by treating 3,6-dichloropyridazine with various 2-hydroxyethylamines following by imidazole ring formation under Swern oxidative conditions. Some mechanistic aspects of the cyclization step are discussed.
